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The beauty of gold: knowledge of mechanisms leads to different applications of organogold compounds in medicine and catalysis

Casini, Angela and Thomas, Sophie R. 2021. The beauty of gold: knowledge of mechanisms leads to different applications of organogold compounds in medicine and catalysis. Chemistry Letters 50 (8) , pp. 1516-1522. 10.1246/cl.210238

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Abstract

This review is aimed at providing a concise overview of the results obtained by our group in the field of organometallic chemistry of gold. Therefore, a selection of examples amongst the most extensively explored families of bioactive gold complexes — Au(I) N-heterocyclic carbenes and cyclometalated Au(III) compounds — is presented. Insights into the bio-inorganic mechanisms of reactivity of organogold compounds obtained by an integrated investigational approach, and knowledge of structure-activity relationships are discussed also in relation to novel applications of gold-based catalysts and metal-mediated transformations in aqueous environment.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Publisher: Chemical Society of Japan
ISSN: 0366-7022
Funders: EPSRC
Date of First Compliant Deposit: 9 August 2021
Date of Acceptance: 6 May 2021
Last Modified: 07 Oct 2021 23:49
URI: http://orca.cardiff.ac.uk/id/eprint/143248

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