The beauty of gold: knowledge of mechanisms leads to different applications of organogold compounds in medicine and catalysis

Casini, Angela ORCID: https://orcid.org/0000-0003-1599-9542 and Thomas, Sophie R. 2021. The beauty of gold: knowledge of mechanisms leads to different applications of organogold compounds in medicine and catalysis. Chemistry Letters 50 (8) , pp. 1516-1522. 10.1246/cl.210238

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Abstract

This review is aimed at providing a concise overview of the results obtained by our group in the field of organometallic chemistry of gold. Therefore, a selection of examples amongst the most extensively explored families of bioactive gold complexes — Au(I) N-heterocyclic carbenes and cyclometalated Au(III) compounds — is presented. Insights into the bio-inorganic mechanisms of reactivity of organogold compounds obtained by an integrated investigational approach, and knowledge of structure-activity relationships are discussed also in relation to novel applications of gold-based catalysts and metal-mediated transformations in aqueous environment.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Publisher:	Chemical Society of Japan
ISSN:	0366-7022
Funders:	EPSRC
Date of First Compliant Deposit:	9 August 2021
Date of Acceptance:	6 May 2021
Last Modified:	10 Nov 2023 08:46
URI:	https://orca.cardiff.ac.uk/id/eprint/143248

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