LIPID MAPS: Update to databases and tools for the lipidomics community

Conroy, Matthew J., Andrews, Robert M., Andrews, Simon, Cockayne, Lauren, Dennis, Edward A., Fahy, Eoin, Gaud, Caroline, Griffiths, William J., Jukes, Geoff, Kolchin, Maksim, Mendivelso, Karla, Lopez-Clavijo, Andrea F., Ready, Caroline, Subramaniam, Shankar and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2023. LIPID MAPS: Update to databases and tools for the lipidomics community. Nucleic Acids Research , gkad896. 10.1093/nar/gkad896

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Abstract

LIPID MAPS (LIPID Metabolites and Pathways Strategy), www.lipidmaps.org, provides a systematic and standardized approach to organizing lipid structural and biochemical data. Founded 20 years ago, the LIPID MAPS nomenclature and classification has become the accepted community standard. LIPID MAPS provides databases for cataloging and identifying lipids at varying levels of characterization in addition to numerous software tools and educational resources, and became an ELIXIR-UK data resource in 2020. This paper describes the expansion of existing databases in LIPID MAPS, including richer metadata with literature provenance, taxonomic data and improved interoperability to facilitate FAIR compliance. A joint project funded by ELIXIR-UK, in collaboration with WikiPathways, curates and hosts pathway data, and annotates lipids in the context of their biochemical pathways. Updated features of the search infrastructure are described along with implementation of programmatic access via API and SPARQL. New lipid-specific databases have been developed and provision of lipidomics tools to the community has been updated. Training and engagement have been expanded with webinars, podcasts and an online training school.

Item Type:	Article
Date Type:	Published Online
Status:	Published
Schools:	Medicine
Publisher:	Oxford University Press
ISSN:	0305-1048
Funders:	Wellcome Trust
Date of First Compliant Deposit:	24 November 2023
Date of Acceptance:	4 October 2023
Last Modified:	17 Jan 2024 14:44
URI:	https://orca.cardiff.ac.uk/id/eprint/164356

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