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Freeman, Bruce A., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Schopfer, Francisco J. 2018. The discovery of nitro-fatty acids as products of metabolic and inflammatory reactions and mediators of adaptive cell signaling. Nitric Oxide: Biology and Chemistry 77 , pp. 106-111. 10.1016/j.niox.2018.05.002 |
Slatter, David A., Percy, Charles L., Allen-Redpath, Keith, Gajsiewicz, Joshua M., Brooks, Nick J., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Tyrrell, Victoria J., Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Lauder, Sarah N., Watson, Andrew, Dul, Maria ORCID: https://orcid.org/0000-0002-0192-2280, Garcia-Diaz, Yoel, Aldrovandi, Maceler, Heurich, Meike, Hall, Judith ORCID: https://orcid.org/0000-0002-6770-7372, Morrissey, James H., Lacroix-Desmazes, Sebastien, Delignat, Sandrine, Jenkins, P. Vincent, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2018. Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies. JCI Insight 3 (6) , e98459. 10.1172/jci.insight.98459 |
Walker, Jaqui, Hutchison, Pippa, Ge, Junbo, Zhao, Dong, Wang, Yongjun, Rothwell, Peter M, Gaziano, J Michael, Chan, Andrew, Burn, John, Chia, John, Langley, Ruth, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Rocca, Bianca and Hawkey, Chris 2018. Aspirin: 120 years of innovation. A report from the 2017 Scientific Conference of the International Aspirin Foundation, 14 September 2017, Charité, Berlin. ecancermedicalscience 12 , 813. 10.3332/ecancer.2018.813 |
Aldrovandi, Maceler, Banthiya, Swathi, Meckelmann, Sven, Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291, Heydeck, Dagmar, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Kuhn, Hartmut 2018. Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1863 (2) , pp. 152-164. 10.1016/j.bbalip.2017.11.005 |
Zhao, Jingmin, Minami, Yoshinori, Etling, Emily, Coleman, John M., Lauder, Sarah, Tyrrell, Victoria, Aldrovandi, Maceler, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Claesson, Hans-Erik, Kagan, Valerian and Wenzel, Sally 2017. Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology 57 (6) 10.1165/rcmb.2017-0031OC |
Lue, H-W, Podolak, J, Kolahi, K, Cheng, L, Rao, S, Garg, D, Xue, C-H, Rantala, J, Tyner, J, Thornburg, K, Martinez-Acevedo, A, Liu, J-J, Amling, C, Truillet, C, Evans, M, O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Nomura, D, Drake, J, Ritz, A and Thomas, G 2017. Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade. Genes and Development 31 , pp. 2067-2084. 10.1101/gad.305292.117 |
Uderhardt, Stefan, Ackermann, Jochen, Fillep, Tobias, Hammond, Victoria J., Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R., Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Diete, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324, Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L., Lee, James J., Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Krönke, Gerhard 2017. Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis and thrombotic disease. Journal of Experimental Medicine 214 (7) , pp. 2121-2138. 10.1084/jem.20161070 |
O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Murphy, Robert C. 2017. Directing eicosanoid esterification into phospholipids. Journal of Lipid Research 58 (5) , pp. 837-839. 10.1194/jlr.C075986 |
O'Connor, Anne ORCID: https://orcid.org/0000-0003-2268-4231, Brasher, Christopher, Slatter, David, Meckelmann, Sven, Hawksworth, Jade, Allen, Stuart ORCID: https://orcid.org/0000-0003-1776-7489 and O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460 2017. LipidFinder: a computational workflow for discovery of lipids identifies eicosanoid-phosphoinositides in platelets. JCI Insight 2 (7) , e91634. 10.1172/jci.insight.91634 |
Aldrovandi, MacEler, Hinz, Christine, Lauder, Sarah N, Podmore, Helen, Hornshaw, Martin, Slatter, David A, Tyrrell, Victoria J, Clark, Stephen R, Marnett, Lawrence J., Collins, Peter W ORCID: https://orcid.org/0000-0002-6410-1324, Murphy, Robert C and O'Donnell, Valerie B ORCID: https://orcid.org/0000-0003-4089-8460 2017. DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression. Redox Biology 11 , pp. 663-672. 10.1016/j.redox.2017.01.001 |
Lauder, Sarah N., Tyrrell, Victoria J., Allen-Redpath, Keith, Aldrovandi, MacEler, Gray, David, Collins, Peter ORCID: https://orcid.org/0000-0002-6410-1324, Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460 2017. Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo. Wellcome Open Research 2 (1) 10.12688/wellcomeopenres.10308.1 |
Stokes, C. A., Kaur, R., Edwards, M R, Mondhe, Madhav, Robinson, D., Prestwich, E. C., Hume, R. D., Marshall, C. A., Perrie, Y., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Sabroe, I. and Parker, L. C. 2016. Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes. Mucosal Immunology 9 (5) , pp. 1303-1316. 10.1038/mi.2015.137 |
Chiba, Takahito, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Calcutt, M. Wade, Boeglin, William E., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Brash, Alan R. 2016. The precise structures and stereochemistry of trihydroxy-linoleates esterified in human and porcine epidermis and their significance in skin barrier function: Implication of an epoxide hydrolase in the transformations of linoleate. Journal of Biological Chemistry 291 (28) , pp. 14540-14544. 10.1074/jbc.M115.711267 |
Bascoul-Colombo, Cécile, Guschina, Irina A., Maskrey, Benjamin H., Good, Mark ORCID: https://orcid.org/0000-0002-1824-1203, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 2016. Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1861 (6) , pp. 524-537. 10.1016/j.bbalip.2016.03.005 |
Hinz, Christine, Aldrovandi, Maceler, Uhlson, Charis, Marnett, Lawrence J., Longhurst, Hilary J., Warner, Timothy D., Alam, Saydul, Slatter, David A., Lauder, Sarah N., Allen-Redpath, Keith, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2016. Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid. Journal of Biological Chemistry 291 (26) , pp. 13448-13464. 10.1074/jbc.M115.700609 |
Slatter, David A., Aldrovandi, Maceler, O'Connor, Anne ORCID: https://orcid.org/0000-0003-2268-4231, Allen, Stuart M., Brasher, Christopher J., Murphy, Robert C., Mecklemann, Sven, Ravi, Saranya, Darley-Usmar, Victor and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2016. Mapping the human platelet lipidome reveals cytosolic phospholipase A2 as a regulator of mitochondrial bioenergetics during activation. Cell Metabolism 23 (5) , pp. 930-944. 10.1016/j.cmet.2016.04.001 |
Jones, Victoria, Birrell, Mark, Maher, Sarah, Griffiths, Mark, Grace, Megan, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671 and Belisi, Maria 2016. Role of Ep2 and Ep4 receptors in airway microvascular leak induced by prostaglandin E2. British Journal of Pharmacology 173 (6) , pp. 992-1004. 10.1111/bph.13400 |
Freeman, Phillip, Moschonas, Konstantinos, Hinz, Christine, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Kinnaird, Tim D., James, Philip E. and Anderson, Richard A. 2015. Changes in platelet function independent of pharmacotherapy following coronary intervention in non-ST-elevation myocardial infarction patients. Atherosclerosis 243 (1) , pp. 320-327. 10.1016/j.atherosclerosis.2015.09.024 |
McCully, Michelle L., Collins, Paul J., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Billen, Jaak, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572 2015. Skin metabolites define a new paradigm in the localization of skin tropic memory T cells. Journal of Immunology 195 (1) , pp. 96-104. 10.4049/jimmunol.1402961 |
Percy, Charles L., Hartmann, Rudolf, Jones, Rhidian M., Balachandran, Subramaniam, Mehta, Dheeraj, Dockal, Michael, Scheiflinger, Friedrich, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Hall, Judith Elizabeth ORCID: https://orcid.org/0000-0002-6770-7372 and Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 2015. Correcting thrombin generation ex vivo using different haemostatic agents following cardiac surgery requiring the use of cardiopulmonary bypass. Blood Coagulation and Fibrinolysis 26 (4) , pp. 357-367. 10.1097/MBC.0000000000000243 |
Ravi, Saranya, Chacko, Balu, Sawada, Hirotaka, Kramer, Philip A., Johnson, Michelle S., Benavides, Gloria A., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Marques, Marisa B. and Darley-Usmar, Victor M. 2015. Metabolic plasticity in resting and thrombin activated platelets. PLoS ONE 10 (4) , e0123597. 10.1371/journal.pone.0123597 |
Morgan, Alwena H., Hammond, Victoria J., Sakoh-Nakatogawa, Machiko, Ohsumi, Yoshinori, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Blanchet, Fabien, Piguet, Vincent, Kiselyov, Kirill and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2015. A novel role for 12/15-lipoxygenase in regulating autophagy. Redox Biology 4 , pp. 40-47. 10.1016/j.redox.2014.11.005 |
Friedmann Angeli, Jose Pedro, Schneider, Manuela, Proneth, Bettina, Tyurina, Yulia Y., Tyurin, Vladimir A., Hammond, Victoria J., Herbach, Nadja, Aichler, Michaela, Walch, Axel, Eggenhofer, Elke, Basavarajappa, Devaraj, Rådmark, Olof, Kobayashi, Sho, Seibt, Tobias, Beck, Heike, Neff, Frauke, Esposito, Irene, Wanke, Rüdiger, Förster, Heidi, Yefremova, Olena, Heinrichmeyer, Marc, Bornkamm, Georg W., Geissler, Edward K., Thomas, Stephen B., Stockwell, Brent R., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Kagan, Valerian E., Schick, Joel A. and Conrad, Marcus 2014. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nature Cell Biology 16 , pp. 1180-1191. 10.1038/ncb3064 |
Mathie, S. A., Dixon, K. L., Walker, S. A., Tyrell, Victoria Jayne, Mondhe, M., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Gregory, L. G. and Lloyd, C. M. 2014. Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge. Allergy 70 (1) , pp. 80-89. 10.1111/all.12536 |
O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Murphy, Robert C. and Watson, Steve P. 2014. Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets. Circulation Research 114 (7) , pp. 1185-1203. 10.1161/CIRCRESAHA.114.301597 |
Aldrovandi, Maceler, Hammond, Victoria Jayne, Podmore, Helen, Hornshaw, Martin, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Marnett, Lawrence J., Slatter, David, Murphy, Robert C., Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2013. Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation. Journal of Lipid Research 54 (11) , pp. 3085-3097. 10.1194/jlr.M041533 |
Pauling, J. D., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Mchugh, N. J. 2013. The contribution of platelets to the pathogenesis of Raynaud's phenomenon and systemic sclerosis. Platelets 24 (7) , pp. 503-515. 10.3109/09537104.2012.719090 |
Bonilla, L., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Rubbo, H. and Trostchansky, A. 2013. Regulation of protein kinase C by nitroarachidonic acid: impact on human platelet activation. Archives of Biochemistry and Biophysics 533 (1-2) , pp. 55-61. 10.1016/j.abb.2013.03.001 |
Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Hammond, Victoria Jayne, Aldrovandi, Maceler, Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Hart, Keith William, Murphy, Robert C., Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2013. Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation. Proceedings of the National Academy of Sciences of the United States of America 110 (15) , pp. 5875-5880. 10.1073/pnas.1222419110 |
Aldrovandi, Maceler and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2013. Oxidized PLs and vascular inflammation. Current Atherosclerosis Reports 15 (5) , pp. 1989-1996. 10.1007/s11883-013-0323-y |
Hammond, Victoria Jayne, Morgan, Alwena H., Lauder, Sarah Nicol, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Brown, Sarah, Freeman, Bruce A., Lloyd, Clare M., Davies, Jane, Bush, Andrew, Levonen, Anna-Liisa, Kansanen, Emilia, Villacorta, Luis, Chen, Y. Eugene, Porter, Ned, Garcia-Diaz, Yoel M., Schopfer, Francisco J. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ. Journal of Biological Chemistry 287 (50) , pp. 41651-41666. 10.1074/jbc.M112.405407 |
Hammond, Victoria Jayne and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Esterified eicosanoids: generation, characterization and function. Biochimica et Biophysica Acta - Biomembranes 1818 (10) , pp. 2403-2412. 10.1016/j.bbamem.2011.12.013 |
Reynolds, Sophie Leanne, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Williams, H., Smale, Shaun, Stephenson, Hayden J., Amos, Nick, George, S. J., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Lang, Derek 2012. Contractile, but not endothelial, dysfunction in early inflammatory arthritis: a possible role for matrix metalloproteinase-9. British Journal of Pharmacology 167 (3) , pp. 505-514. 10.1111/j.1476-5381.2012.01988.x |
O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Murphy, Robert C. 2012. New families of bioactive oxidized phospholipids generated by immune cells: Identification and signaling actions. Blood 120 (10) , pp. 1985-1992. 10.1182/blood-2012-04-402826 |
Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Oxidized phospholipid signaling in immune cells. Current Opinion in Pharmacology 12 (4) , pp. 471-477. 10.1016/j.coph.2012.02.013 |
Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Heydeck, Dagmar, Jones, Gareth Wyn, Kronke, Gerhard, Funk, Colin D., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Adams, Deborah, Kuhn, Hartmut and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Development of myeloproliferative disease in 12/15-lipoxygenase deficiency [Letter]. Blood 119 (25) , pp. 6173-6174. 10.1182/blood-2012-02-410928 |
O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2011. Mass spectrometry analysis of oxidized phosphatidylcholine and phosphatidylethanolamine. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1811 (11) , pp. 818-826. 10.1016/j.bbalip.2011.07.018 |
Ruge, Fiona, Glavini, Aikaterini, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Richards, Hannah E., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Philpott, Michael P. and Porter, Rebecca ORCID: https://orcid.org/0000-0001-6748-0916 2011. Delineating immune-mediated mechanisms underlying hair follicle destruction in the mouse mutant defolliculated. Journal of Investigative Dermatology 131 (3) , pp. 572-579. 10.1038/jid.2010.379 |
Zhao, Jinming, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Balzar, Silvana, St. Croix, Claudette M., Trudeau, John B. and Wenzel, Sally E. 2011. 15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells. Proceedings of the National Academy of Sciences of the United States of America 108 (34) , pp. 14246-14251. 10.1073/pnas.1018075108 |
Trostchansky, A., Bonilla, L., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Marnett, L. J., Radi, R. and Rubbo, H. 2011. Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2. Journal of Biological Chemistry 286 (15) , pp. 12891-12900. 10.1074/jbc.M110.154518 |
Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Morgan, Lloyd T., Maskrey, Ben, Murphy, Robert C., Kuhn, Hartmut, Hazen, Stanley L., Goodall, Alison H., Hamali, Hassan A., Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2010. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. Journal of Biological Chemistry 285 (10) , pp. 6891-6903. 10.1074/jbc.M109.078428 |
Morgan, Alwena Haf, Hammond, Victoria Jayne, Morgan, Lloyd, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Tallman, Keri A., Garcia-Diaz, Yoel Ruslan, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Porter, Ned A., Murphy, Robert C. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2010. Quantitative assays for esterified oxylipins generated by immune cells. Nature Protocols 5 (12) , pp. 1919-1931. 10.1038/nprot.2010.162 |
Ivanov, Igor, Heydeck, Dagmar, Hofheinz, Katharina, Roffeis, Jana, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Kuhn, Hartmut and Walther, Matthias 2010. Molecular enzymology of lipoxygenases. Archives of biochemistry and biophysics 503 (2) , pp. 161-174. 10.1016/j.abb.2010.08.016 |
Morgan, Lloyd T., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Kühn, Hartmut and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2010. Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase. Biochemical Journal 431 (1) , pp. 141-148. 10.1042/BJ20100415 |
Tull, Samantha P., Yates, Clara M., Maskrey, Ben, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Madden, Jackie, Grimble, Robert F., Calder, Philip C., Nash, Gerard B. and Rainger, G. Ed. 2009. Omega-3 fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment. PLoS Biology 7 (8) , e1000177. 10.1371/journal.pbio.1000177 |
Rubbo, Homero, Trostchansky, Andrés and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2009. Peroxynitrite-mediated lipid oxidation and nitration: mechanisms and consequences. Archives of Biochemistry and Biophysics 484 (2) , pp. 167-172. 10.1016/j.abb.2008.11.007 |
Ferreira, Ana M., Ferrari, Mariana I., Trostchansky, Andrés, Batthyany, Carlos, Souza, José M., Alvarez, María N., López, Gloria V., Baker, Paul R. S., Schopfer, Francisco J., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Freeman, Bruce A. and Rubbo, Homero 2009. Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate. Biochemical Journal 417 (1) , pp. 223-234. 10.1042/BJ20080701 |
Maskrey, B. H., Bermudez-Fajardo, A., Morgan, Alwena Haf, Stewart-Jones, Esther, Dioszeghy, Vincent, Taylor, G. W., Baker, P. R. S., Coles, Barbara, Coffey, Marcus Jonathan, Kuhn, H. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2009. Activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase [Addition]. Journal of Biological Chemistry 284 (37) , p. 25460. 10.1074/jbc.A611776200 |
Morgan, Alwena Haf, Dioszeghy, Vincent, Maskrey, Benjamin, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Mathie, Sara A., Lloyd, Clare M., Kuhn, Hartmut, Topley, Nicholas, Coles, Barbara, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2009. Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. Journal of Biological Chemistry 284 (32) , pp. 21185-21191. 10.1074/jbc.M109.021634 |
Baker, Paul R. S., Schopfer, Francisco J., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Freeman, Bruce A. 2009. Convergence of nitric oxide and lipid signaling: anti-inflammatory nitro-fatty acids. Free Radical Biology & Medicine 46 (8) , pp. 989-1003. 10.1016/j.freeradbiomed.2008.11.021 |
Gregory, L. G., Causton, B., Murdoch, J. R., Mathie, S. A., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Priest, F. M., Quint, D. J. and Lloyd, C. M. 2009. Inhaled house dust mite induces pulmonary T helper 2 cytokine production. Clinical and Experimental Allergy 39 (10) , pp. 1597-1610. 10.1111/j.1365-2222.2009.03302.x |
Zhao, Jinming, Maskrey, Ben, Balzar, Silvana, Chibana, Kazuyuki, Mustovich, Anthony, Hu, Haizhen, Trudeau, John B., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Wenzel, Sally E. 2009. Interleukin-13-induced MUC5AC is regulated by 15-Lipoxygenase 1 pathway in human bronchial epithelial cells. American Journal of Respiratory and Critical Care Medicine 179 (9) , pp. 782-790. 10.1164/rccm.200811-1744OC |
Morton, Jonathan, Coles, Barbara, Wright, Kate Louise, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Morrow, Jason D., Terry, Erin S., Anning, Peter, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Dioszeghy, Vincent, Kuhn, Hartmut, Chaitidis, Pavlos, Hobbs, Adrian J., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2008. Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFN -dependent iNOS expression in the vasculature of healthy mice. Blood 111 (10) , pp. 5187-5194. 10.1182/blood-2007-10-117283 |
Dioszeghy, Vincent, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Maskrey, Benjamin H., Colmont, Chantal Sophie, Topley, Nicholas, Chaitidis, Pavlos, Kühn, Hartmut, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2008. 12/15-lipoxygenase regulates the inflammatory response to bacterial products in vivo. The Journal of Immunology 181 (9) , pp. 6514-6524. |
Coles, Barbara, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Rose-John, Stefan, Scheller, J., Jones, S. A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2007. Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo. American Journal of Pathology 171 (1) , pp. 315-325. 10.2353/ajpath.2007.061078 |
Anning, Peter Brian, Coles, Barbara, Morton, Jonathan, Wang, Haibin, Uddin, Jashim, Morrow, Jason D., Dey, Sudhansu K., Marnett, Lawrence J. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2006. Nitric Oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors. Blood 108 (13) , pp. 4059-4062. 10.1182/blood-2006-02-005330 |
Williams, Paula Claire, Coffey, Marcus Jonathan, Coles, Barbara, Sanchez, Stephanie, Morrow, Jason D., Cockcroft, John Ronald, Lewis, Malcolm John and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2005. In vivo aspirin supplementation inhibits nitric oxide consumption by human platelets. Blood 106 (8) , pp. 2737-2743. 10.1182/blood-2005-02-0664 |
Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Anning, Peter Brian, Coffey, Marcus Jonathan, Roberts, Andrew Glyn, Marnett, Lawrence J. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2005. Depletion of iNOS-derived nitric oxide by prostaglandin H synthase-2 in inflammation-activated J774.2 macrophages through lipohydroperoxidase turnover. Biochemical Journal 385 (3) , pp. 815-821. 10.1042/BJ20041353 |
Coffey, Marcus Jonathan, Coles, Barbara, Locke, Matthew, Bermudez-Fajardo, Alexandra, Williams, Paula Claire, Jarvis, Gavin E. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2004. Interactions of 12-lipoxygenase with phospholipase A2 isoforms following platelet activation through the glycoprotein VI collagen receptor. FEBS Letters 576 (1-2) , pp. 165-168. 10.1016/j.febslet.2004.09.007 |
Coffey, Marcus Jonathan, Jarvis, Gavin E, Gibbins, Jonathan M., Coles, Barbara, Barrett, Natasha E., Wylie, Oliver R.E. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2004. Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis. Circulation Research 94 (12) , pp. 1598-1605. 10.1161/01.RES.0000132281.78948.65 |
Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Coffey, Marcus Jonathan, McLean, Rhona Murray, Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324, Lewis, Malcolm John, Cross, Andrew R. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2002. Characterization of nitric oxide consumption pathways by normal, chronic granulomatous disease and myeloperoxidase-deficient human neutrophils. The Journal of Immunology 169 (10) , pp. 5889-5896. |
Coles, Barbara, Bloodsworth, Allison, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Lewis, Malcolm John, Cross, Andrew R., Freeman, Bruce A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2002. Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells. Circulation Research 91 (5) , pp. 375-381. 10.1161/01.RES.0000032114.68919.EF |
Coffey, Marcus Jonathan, Natarajan, Rama, Chumley, Philip H., Coles, Barbara, Thimmalapura, Pushpa-Rekha, Nowell, Mari Ann, Kühn, Hartmut, Lewis, Malcolm John, Freeman, Bruce A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2001. Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 98 (14) , pp. 8006-8011. 10.1073/pnas.141136098 |