Protty, Majd B., Tyrrell, Victoria J., Allen-Redpath, Keith, Soyama, Shin, Hajeyah, Ali A., Costa, Daniela ORCID: https://orcid.org/0000-0001-8821-5898, Choudhury, Anirban, Mitra, Rito, Sharman, Amal, Yaqoob, Parveen, Jenkins, P. Vince, Yousef, Zaheer, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2024. Thrombin generation is associated with extracellular vesicle and leukocyte lipid membranes in atherosclerotic cardiovascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology 44 (9) , pp. 2038-2052. 10.1161/ATVBAHA.124.320902 |
Kopczynski, Dominik, Ejsing, Christer S., McDonald, Jeffrey G., Bamba, Takeshi, Baker, Erin S., Bertrand-Michel, Justine, Brügger, Britta, Coman, Cristina, Ellis, Shane R., Garrett, Timothy J., Griffiths, William J., Guan, Xue Li, Han, Xianlin, Höring, Marcus, Holcapek, Michal, Hoffmann, Nils, Huynh, Kevin, Lehmann, Rainer, Jones, Jace W., Kaddurah-Daouk, Rima, Köfeler, Harald C., Meikle, Peter J., Metz, Thomas O., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Saigusa, Daisuke, Schwudke, Dominik, Shevchenko, Andrej, Torta, Federico, Vizcaíno, Juan Antonio, Welti, Ruth, Wenk, Markus R., Wolrab, Denise, Xia, Yu, Ekroos, Kim, Ahrends, Robert and Liebisch, Gerhard 2024. The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data. Journal of Lipid Research 65 (9) , 100621. 10.1016/j.jlr.2024.100621 |
Parchem, Karol, Letsiou, Sophia, Petan, Toni, Oskolkova, Olga, Medina, Isabel, Kuda, Ondrej, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Nicolaou, Anna, Fedorova, Maria, Bochkov, Valery and Gladine, Cécile 2024. Oxylipin profiling for clinical research: Current status and future perspectives. Progress in Lipid Research 95 , 101276. 10.1016/j.plipres.2024.101276 |
Hajeyah, Ali A., Protty, Majd B., Paul, Divyani, Costa, Daniela ORCID: https://orcid.org/0000-0001-8821-5898, Omidvar, Nader, Morgan, Bethan, Iwasaki, Yugo, McGill, Beth, Jenkins, P. Vincent, Yousef, Zaheer, Allen-Redpath, Keith, Soyama, Shin, Choudhury, Anirban, Mitra, Rito, Yaqoob, Parveen, Morrissey, James H., Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2024. Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease. Journal of Lipid Research 65 (1) , 100484. 10.1016/j.jlr.2023.100484 |
Allen, Naoimi, Lacey, Ben, Lawlor, Deborah, Pell, Jill, Gallacher, John, Smeeth, Liam, Elliott, Paul, Matthews, Paul, Lyons, Ronan, Whetton, Anthony, Lucassen, Anneke, Hurles, Matthew, Chapman, Michael, Roddam, Andrew, Fitzpatrick, Natalie, Hansell, Anna, Hardy, Rebecca, Marioni, Riccardo, O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Lindgren, Cecilia, Effingham, Mark, Sellors, Jonathan, Danesh, John and Collins, Rory 2024. Prospective study design and data analysis in UK Biobank. Science Translational Medicine 16 (729) , eadf4428. 10.1126/scitranslmed.adf4428 |
Witting, Michael, Malik, Adnan, Leach, Andrew, Bridge, Alan, Aimo, Lucila, Conroy, Matthew J., O’Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Hoffmann, Nils, Kopczynski, Dominik, Giacomoni, Franck, Paulhe, Nils, Gassiot, Amaury Cazenave, Poupin, Nathalie, Jourdan, Fabien and Bertrand-Michel, Justine 2024. Challenges and perspectives for naming lipids in the context of lipidomics. Metabolomics 20 (1) , 15. 10.1007/s11306-023-02075-x |
O’Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Schebb, Nils H., Milne, Ginger L., Murphy, Michael P., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Steinhilber, Dieter, Gelhaus, Stacy L., Kühn, Hartmut, Gelb, Michael H., Jakobsson, Per-Johan, Blair, Ian A., Murphy, Robert C., Freeman, Bruce A., Brash, Alan R. and FitzGerald, Garret A. 2023. Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples. Nature Communications 14 (1) , 7172. 10.1038/s41467-023-41766-w |
Conroy, Matthew J., Andrews, Robert M., Andrews, Simon, Cockayne, Lauren, Dennis, Edward A., Fahy, Eoin, Gaud, Caroline, Griffiths, William J., Jukes, Geoff, Kolchin, Maksim, Mendivelso, Karla, Lopez-Clavijo, Andrea F., Ready, Caroline, Subramaniam, Shankar and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2023. LIPID MAPS: Update to databases and tools for the lipidomics community. Nucleic Acids Research , gkad896. 10.1093/nar/gkad896 |
Schönichen, Claudia, Montague, Samantha J., Brouns, Sanne L.N., Burston, James J., Cosemans, Judith M.E.M., Jurk, Kerstin, Kehrel, Beate E., Koenen, Rory R., Ní Áinle, Fionnuala, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Soehnlein, Oliver, Watson, Steve P., Kuijpers, Marijke J.E., Heemskerk, Johan W.M. and Nagy, Magdolna 2023. Antagonistic roles of human platelet integrin αIIbβ3 and chemokines in regulating neutrophil activation and fate on arterial thrombi under flow. Arteriosclerosis, Thrombosis, and Vascular Biology 43 , pp. 1700-1712. 10.1161/ATVBAHA.122.318767 |
Czyzowska, Agnieszka, Brown, Jacob, Xu, Hongyang, Sataranatarajan, Kavitha, Kinter, Michael, Tyrell, Victoria J., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Van Remmen, Holly 2023. Elevated phospholipid hydroperoxide glutathione peroxidase (GPX4) expression modulates oxylipin formation and inhibits age-related skeletal muscle atrophy and weakness. Redox Biology 64 , 102761. 10.1016/j.redox.2023.102761 |
Millrine, David, Cardus Figueras, Ana, Uceda Fernandez, Javier, Andrews, Robert, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Cossins, Benjamin, Rice, Christopher M., Li, Jasmine, Tyrrell, Victoria, McLeod, Louise, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Taylor, Philip ORCID: https://orcid.org/0000-0003-0163-1421, Turner, Stephen J., Jenkins, Brendan J., Jones, Gareth, Topley, Nicholas, Williams, Nigel ORCID: https://orcid.org/0000-0003-1177-6931 and Jones, Simon ORCID: https://orcid.org/0000-0001-7297-9711 2023. Th1 cells alter the inflammatory signature of IL-6 by channeling STAT transcription factors to Alu-like retroelements. The Journal of Immunology 211 (2) , pp. 274-286. 10.4049/jimmunol.2300114 |
Sarmad, Sarir, Viant, Mark R., Dunn, Warwick B., Goodacre, Royston, Wilson, Ian D., Chappell, Katie E., Griffin, Julian L., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Naicker, Brendon, Lewis, Matthew R. and Suzuki, Toru 2023. A proposed framework to evaluate the quality and reliability of targeted metabolomics assays from the UK Consortium on Metabolic Phenotyping (MAP/UK). Nature Protocols 10.1038/s41596-022-00801-8 |
O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2023. Lipidomics moves to center stage of biomedicine. Function 4 (1) , zqac071. 10.1093/function/zqac071 |
Ni, Zhixu, Wölk, Michele, Jukes, Geoff, Mendivelso Espinosa, Karla, Ahrends, Robert, Aimo, Lucila, Alvarez-Jarreta, Jorge, Andrews, Simon, Andrews, Robert, Bridge, Alan, Clair, Geremy C., Conroy, Matthew J., Fahy, Eoin, Gaud, Caroline, Goracci, Laura, Hartler, Jürgen, Hoffmann, Nils, Kopczyinki, Dominik, Korf, Ansgar, Lopez-Clavijo, Andrea F., Malik, Adnan, Ackerman, Jacobo Miranda, Molenaar, Martijn R., O?Donovan, Claire, Pluskal, Tomá?, Shevchenko, Andrej, Slenter, Denise, Siuzdak, Gary, Kutmon, Martina, Tsugawa, Hiroshi, Willighagen, Egon L., Xia, Jianguo, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Fedorova, Maria 2022. Guiding the choice of informatics software and tools for lipidomics research applications. Nature Methods 20 (2) , pp. 193-204. 10.1038/s41592-022-01710-0 |
Brown, Jacob L., Peelor, Fredrick F., Georgescu, Constantin, Wren, Jonathan D., Kinter, Michael, Tyrrell, Victoria J., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Miller, Benjamin F. and Van Remmen, Holly 2022. Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy. Redox Biology 57 , 102518. 10.1016/j.redox.2022.102518 |
McDonald, Jeffrey G., Ejsing, Christer S., Kopczynski, Dominik, Holcapek, Michal, Aoki, Junken, Arita, Makoto, Arita, Masanori, Baker, Erin S., Bertrand-Michel, Justine, Bowden, John A., Brügger, Britta, Ellis, Shane R., Fedorova, Maria, Griffiths, William J., Han, Xianlin, Hartler, Jürgen, Hoffmann, Nils, Koelmel, Jeremy P., Köfeler, Harald C., Mitchell, Todd W., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Saigusa, Daisuke, Schwudke, Dominik, Shevchenko, Andrej, Ulmer, Candice Z., Wenk, Markus R., Witting, Michael, Wolrab, Denise, Xia, Yu, Ahrends, Robert, Liebisch, Gerhard and Ekroos, Kim 2022. Introducing the lipidomics minimal reporting checklist. Nature Metabolism 4 (9) , 1086–1088. 10.1038/s42255-022-00628-3 |
Schebb, Nils Helge, Kühn, Hartmut, Kahnt, Astrid S., Rund, Katharina M., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Flamand, Nicolas, Peters-Golden, Marc, Jakobsson, Per-Johan, Weylandt, Karsten H., Rohwer, Nadine, Murphy, Robert C., Geisslinger, Gerd, FitzGerald, Garret A., Hanson, Julien, Dahlgren, Claes, Alnouri, Mohamad Wessam, Offermanns, Stefan and Steinhilber, Dieter 2022. Formation, signaling and occurrence of specialized pro-resolving lipid mediators - What is the evidence so far? Frontiers in Pharmacology 13 , 838782. 10.3389/fphar.2022.838782 |
O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2022. New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease. Biochemical Society Transactions 50 (1) , pp. 1-11. 10.1042/BST20210579 |
Diskin, Ciana, Zotta, Alessia, Corcoran, Sarah E., Tyrrell, Victoria J., Zaslona, Zbigniew, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and O'Neill, Luke A. J. 2021. 4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages. Journal of Immunology 207 (10) , pp. 2561-2569. 10.4049/jimmunol.2100488 |
Diskin, Ciana, Corcoran, Sarah E., Tyrrell, Victoria J., McGettrick, Anne F., Zaslona, Zbigniew, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Nolan, Derek P. and O'Neill, Luke A. J. 2021. The Trypanosome-derived metabolite indole-3-pyruvate inhibits prostaglandin production in macrophages by targeting COX2. Journal of Immunology 207 (10) , pp. 2551-2560. 10.4049/jimmunol.2100402 |
Köfeler, Harald C., Eichmann, Thomas O., Ahrends, Robert, Bowden, John A., Danne-Rasche, Niklas, Dennis, Edward A., Fedorova, Maria, Griffiths, William J., Han, Xianlin, Hartler, Jürgen, Hol?apek, Michal, Jirásko, Robert, Koelmel, Jeremy P., Ejsing, Christer S., Liebisch, Gerhard, Ni, Zhixu, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Quehenberger, Oswald, Schwudke, Dominik, Shevchenko, Andrej, Wakelam, Michael J. O., Wenk, Markus R., Wolrab, Denise and Ekroos, Kim 2021. Quality control requirements for the correct annotation of lipidomics data. Nature Communications 12 (1) , 4771. 10.1038/s41467-021-24984-y |
Chan, Melissa V., Hayman, Melissa A., Sivapalaratnam, Suthesh, Crescente, Marilena, Allan, Harriet E., Edin, Matthew L., Zeldin, Darryl C., Milne, Ginger L., Stephens, Jonathan, Greene, Daniel, Hanif, Moghees, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Dong, Liang, Malkowski, Michael G., Lentaigne, Claire, Wedderburn, Katherine, Stubbs, Matthew, Downes, Kate, Ouwehand, Willem H., Turro, Ernest, NIHR BioResource, Hart, Daniel P., Freson, Kathleen, Laffan, Michael A. and Warner, Timothy D. 2021. Identification of a homozygous recessive variant in PTGS1 resulting in a congenital aspirin-like defect in platelet function. Haematologica 106 (5) , pp. 1423-1432. 10.3324/haematol.2019.235895 |
Alvarez-Jarreta, Jorge, Rodrigues, Patricia R.S., Fahy, Eoin, O'Connor, Anne ORCID: https://orcid.org/0000-0003-2268-4231, Price, Anna, Gaud, Caroline, Andrews, Simon, Benton, Paul, Siuzdak, Gary, Hawksworth, Jade I., Valdivia-Garcia, Maria, Allen, Stuart M. ORCID: https://orcid.org/0000-0003-1776-7489, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Valencia, Alfonso 2021. LipidFinder 2.0: advanced informatics pipeline for lipidomics discovery applications. Bioinformatics 37 (10) , pp. 1478-1479. 10.1093/bioinformatics/btaa856 |
Crittenden, Siobhan, Goepp, Marie, Pollock, Jolinda, Robb, Calum T., Smyth, Danielle J., Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291, Andrews, Robert, Tyrrell, Victoria, Gkikas, Konstantinos, Adima, Alexander, O'Connor, Richard A., Davies, Luke, Li, Xue-Feng, Yao, Hatti X., Ho, Gwo-Tzer, Zheng, Xiaozhong, Mair, Amil, Vermeren, Sonja, Qian, Bin-Zhi, Mole, Damian J., Gerasimidis, Konstantinos, Schwarze, Jürgen K. J., Breyer, Richard M., Arends, Mark J., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Iredale, John P., Anderton, Stephen M., Narumiya, Shuh, Maizels, Rick M., Rossi, Adriano G., Howie, Sarah E. and Yao, Chengcan 2021. Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells. Science Advances 7 (7) , eabd7954. 10.1126/sciadv.abd7954 |
Gaud, Caroline, Sousa, Bebiana C., Nguyen, An, Fedorova, Maria, Ni, Zhixu, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Wakelam, Michael J.O., Andrews, Simon and Lopez-Clavijo, Andrea F. 2021. BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS. F1000Research 10 (4) 10.12688/f1000research.28022.1 |
Tyrrell, Victoria J., Ali, Faraz, Boeglin, William E., Andrews, Robert, Burston, James, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Ingram, John R., Murphy, Robert C., Piguet, Vincent, Brash, Alan R., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 2021. Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions. Journal of Lipid Research 62 , 100094. 10.1016/j.jlr.2021.100094 |
Liebisch, Gerhard, Fahy, Eoin, Aoki, Junken, Dennis, Edward A., Durand, Thierry, Ejsing, Christer, Fedorova, Maria, Feussner, Ivo, Griffiths, William J., Koefeler, Harald, Merrill, Alfred H., Murphy, Robert C., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Oskolkova, Olga V., Subramaniam, Shankar, Wakelam, Michael and Spener, Friedrich 2020. Update on LIPID MAPS classification, nomenclature and shorthand notation for MS-derived lipid structures. Journal of Lipid Research 61 , pp. 1539-1555. 10.1194/jlr.S120001025 |
Hajeyah, Ali A., Griffiths, William J., Wang, Yuqin, Finch, Andrew J. and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2020. The biosynthesis of enzymatically oxidized lipids. Frontiers in Endocrinology 11 , 591819. 10.3389/fendo.2020.591819 |
O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, FitzGerald, Garret A., Murphy, Robert C., Liebisch, Gerhard, Dennis, Edward A., Quehenberger, Oswald, Subramaniam, Shankar and Wakelam, Michael J.O. 2020. Steps Toward Minimal Reporting Standards for Lipidomics Mass Spectrometry in Biomedical Research Publications. Circulation: Genomic and Precision Medicine 13 (6) , e003019. 10.1161/CIRCGEN.120.003019 |
Ipseiz, Natacha ORCID: https://orcid.org/0000-0001-5008-8889, Pickering, Robert J., Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Tyrrell, Victoria J., Davies, Luke C., Orr, Selinda J., Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095, Fathalla, Dina, Robertson, Avril A. B., Bryant, Clare E., O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460 and Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 2020. Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway. EMBO Journal 39 (14) , e103454. 10.15252/embj.2019103454 |
Meckelmann, Sven W., Hawksworth, Jade I., White, Daniel, Andrews, Robert, Rodrigues, Patricia, O'Connor, Anne ORCID: https://orcid.org/0000-0003-2268-4231, Alvarez-Jarreta, Jorge, Tyrrell, Victoria J., Hinz, Christine, Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Aldrovandi, Maceler, Watkins, William J. ORCID: https://orcid.org/0000-0003-3262-6588, Engler, Adam J., Lo Sardo, Valentina, Slatter, David A., Allen, Stuart M. ORCID: https://orcid.org/0000-0003-1776-7489, Acharya, Jay, Mitchell, Jacquie, Cooper, Jackie, Aoki, Junken, Kano, Kuniyuki, Humphries, Steve E. and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2020. Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274. Circulation: Genomic and Precision Medicine 13 (3) , pp. 149-164. 10.1161/CIRCGEN.119.002806 |
Doll, Sebastian, Freitas, Florencio Porto, Shah, Ron, Aldrovandi, Maceler, Costa da Silva, Milene, Ingold, Irina, Grocin, Andrea Goya, Xavier da Silva, Thamara Nishida, Panzilius, Elena, Scheel, Christina H., Mourão, André, Buday, Katalin, Sato, Mami, Wanninger, Jonas, Vignane, Thibaut, Mohana, Vaishnavi, Rehberg, Markus, Flatley, Andrew, Schepers, Aloys, Kurz, Andreas, White, Daniel, Sauer, Markus, Sattler, Michael, Tate, Edward William, Schmitz, Werner, Schulze, Almut, O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Proneth, Bettina, Popowicz, Grzegorz M., Pratt, Derek A., Friedmann Angeli, José Pedro and Conrad, Marcus 2019. FSP1 is a glutathione-independent ferroptosis suppressor. Nature 575 , pp. 693-698. 10.1038/s41586-019-1707-0 |
Gallagher, Hayley, Williams, Jessica O., Ferekidis, Nele, Ismail, Alaa, Chan, Yee-Hung, Michael, Daryn R., Guschina, Irina A., Tyrrell, Victoria J., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Khozin-Goldberg, Inna, Boussiba, Sammy and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2019. Dihimo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. BBA - Molecular Basis of Disease 1865 (9) , pp. 2538-2550. 10.1016/j.bbadis.2019.06.011 |
Hinz, Christine, Liggi, Sonia, Mocciaro, Gabriele, Jung, Stephanie M., Induruwa, Isuru, Pereira, Milton C.D.A., Bryant, Clare E., Meckelmann, Sven W., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Farndale, Richard W., Fjeldsted, John C. and Griffin, Julian L. 2019. A comprehensive UHPLC ion mobility QTOF method for profiling and quantification of eicosanoids, other oxylipins and fatty acids. Analytical Chemistry 91 (13) , pp. 8025-8035. 10.1021/acs.analchem.8b04615 |
Kornilov, Andrei, Kennedy, Paul D., Aldrovandi, MacEler, Watson, Andrew J. A., Hinz, Christine, Harless, Bryan, Colombo, Joseph, Maxey, Kirk M., Tyrrell, Victoria J., Simon, Matthew, Aggarwal, Varinder K., Boeglin, William E., Brash, Alan R., Murphy, Robert C. and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2019. Revising the structure of a new eicosanoid from human platelets to 8,9-11,12-diepoxy-13- hydroxy-eicosadienoic acid. Journal of Biological Chemistry 294 , pp. 9225-9238. 10.1074/jbc.RA119.008915 |
Allen-Redpath, Keith, Aldrovandi, Maceler, Lauder, Sarah N., Gketsopoulou, Anastasia, Tyrrell, Victoria J., Slatter, David A., Andrews, Robert, Watkins, W. John ORCID: https://orcid.org/0000-0003-3262-6588, Atkinson, Georgia, McNeill, Eileen, Gilfedder, Anna, Protty, Majd, Burston, James, Johnson, Sam R. C., Rodrigues, Patricia R. S. ORCID: https://orcid.org/0000-0003-0768-0013, Jones, Dylan O., Lee, Regent, Handa, Ashok, Channon, Keith, Obaji, Samya, Alvarez-Jarreta, Jorge, Krönke, Gerhard, Ackermann, Jochen, Jenkins, P. Vince, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2019. Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity. Proceedings of the National Academy of Sciences 116 (16) , pp. 8038-8047. 10.1073/pnas.1814409116 |
Evans, Robert J, Pline, Katherine, Loynes, Catherine A., Needs, Sarah, Aldrovandi, Maceler, Tiefenback, Jens, Bielska, Ewa, Rubino, Rachel E., Nicol, Christopher J., May, Robin C., Krause, Henry M., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Renshaw, Stephen A. and Johnstone, Simon A. 2019. 15-keto-prostaglandin E₂ activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection. PLoS Pathogens 15 (3) , e1007597. 10.1371/journal.ppat.1007597 |
O'Donnell, V ORCID: https://orcid.org/0000-0003-4089-8460, Aldrovandi, M, Murphy, R C and Kronke, G 2019. Enzymatically-oxidized phospholipids assume center-stage as essential regulators of innate immunity and cell death. Science Signaling 12 (574) , eaau2293. 10.1126/scisignal.aau2293 |
Fahy, Eoin, Alvarez-Jarreta, Jorge, Brasher, Christopher J., Nguyen, An, Hawksworth, Jade I., Rodrigues, Patricia ORCID: https://orcid.org/0000-0003-0768-0013, Meckelmann, Sven, Allen, Stuart M. ORCID: https://orcid.org/0000-0003-1776-7489 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2019. LipidFinder on LIPID MAPS: peak filtering, MS searching and statistical analysis for lipidomics. Bioinformatics 35 (4) , pp. 685-687. 10.1093/bioinformatics/bty679 |
O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Dennis, Edward A, Wakelam, Michael J O and Subramaniam, Shankar 2019. LIPID MAP: Serving the next generation of lipid researchers with tools, resources, data and training. Science Signaling 12 (563) , eaaw2964. 10.1126/scisignal.aaw2964 |
Vliet, Albert van der, Dick, Tobias P., Aust, Steve D., Koppenol, Willem H., Ursini, Fulvio, Kettle, Antony J., Beckman, Joseph S., O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Darley-Usmar, Victor, Lancaster, Jack, Hogg, Neil, Davies, Kelvin J.A., Forman, Henry Jay and Janssen-Heininger, Yvonne M.W. 2018. Rust never sleeps: the continuing story of the Iron Bolt. Free Radical Biology and Medicine 124 , pp. 353-357. 10.1016/j.freeradbiomed.2018.06.017 |
O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522 and Wakelam, M. J. O. 2018. Phospholipid signaling in innate immune cells. The Journal of Clinical Investigation 128 (7) , pp. 2670-2679. 10.1172/JCI97944 |
Freeman, Bruce A., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Schopfer, Francisco J. 2018. The discovery of nitro-fatty acids as products of metabolic and inflammatory reactions and mediators of adaptive cell signaling. Nitric Oxide: Biology and Chemistry 77 , pp. 106-111. 10.1016/j.niox.2018.05.002 |
Slatter, David A., Percy, Charles L., Allen-Redpath, Keith, Gajsiewicz, Joshua M., Brooks, Nick J., Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Tyrrell, Victoria J., Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Lauder, Sarah N., Watson, Andrew, Dul, Maria ORCID: https://orcid.org/0000-0002-0192-2280, Garcia-Diaz, Yoel, Aldrovandi, Maceler, Heurich, Meike, Hall, Judith ORCID: https://orcid.org/0000-0002-6770-7372, Morrissey, James H., Lacroix-Desmazes, Sebastien, Delignat, Sandrine, Jenkins, P. Vincent, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2018. Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies. JCI Insight 3 (6) , e98459. 10.1172/jci.insight.98459 |
Walker, Jaqui, Hutchison, Pippa, Ge, Junbo, Zhao, Dong, Wang, Yongjun, Rothwell, Peter M, Gaziano, J Michael, Chan, Andrew, Burn, John, Chia, John, Langley, Ruth, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Rocca, Bianca and Hawkey, Chris 2018. Aspirin: 120 years of innovation. A report from the 2017 Scientific Conference of the International Aspirin Foundation, 14 September 2017, Charité, Berlin. ecancermedicalscience 12 , 813. 10.3332/ecancer.2018.813 |
Aldrovandi, Maceler, Banthiya, Swathi, Meckelmann, Sven, Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291, Heydeck, Dagmar, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Kuhn, Hartmut 2018. Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1863 (2) , pp. 152-164. 10.1016/j.bbalip.2017.11.005 |
Zhao, Jingmin, Minami, Yoshinori, Etling, Emily, Coleman, John M., Lauder, Sarah, Tyrrell, Victoria, Aldrovandi, Maceler, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Claesson, Hans-Erik, Kagan, Valerian and Wenzel, Sally 2017. Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology 57 (6) 10.1165/rcmb.2017-0031OC |
Lue, H-W, Podolak, J, Kolahi, K, Cheng, L, Rao, S, Garg, D, Xue, C-H, Rantala, J, Tyner, J, Thornburg, K, Martinez-Acevedo, A, Liu, J-J, Amling, C, Truillet, C, Evans, M, O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Nomura, D, Drake, J, Ritz, A and Thomas, G 2017. Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade. Genes and Development 31 , pp. 2067-2084. 10.1101/gad.305292.117 |
Uderhardt, Stefan, Ackermann, Jochen, Fillep, Tobias, Hammond, Victoria J., Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R., Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Diete, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324, Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L., Lee, James J., Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Krönke, Gerhard 2017. Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis and thrombotic disease. Journal of Experimental Medicine 214 (7) , pp. 2121-2138. 10.1084/jem.20161070 |
O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Murphy, Robert C. 2017. Directing eicosanoid esterification into phospholipids. Journal of Lipid Research 58 (5) , pp. 837-839. 10.1194/jlr.C075986 |
O'Connor, Anne ORCID: https://orcid.org/0000-0003-2268-4231, Brasher, Christopher, Slatter, David, Meckelmann, Sven, Hawksworth, Jade, Allen, Stuart ORCID: https://orcid.org/0000-0003-1776-7489 and O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460 2017. LipidFinder: a computational workflow for discovery of lipids identifies eicosanoid-phosphoinositides in platelets. JCI Insight 2 (7) , e91634. 10.1172/jci.insight.91634 |
Aldrovandi, MacEler, Hinz, Christine, Lauder, Sarah N, Podmore, Helen, Hornshaw, Martin, Slatter, David A, Tyrrell, Victoria J, Clark, Stephen R, Marnett, Lawrence J., Collins, Peter W ORCID: https://orcid.org/0000-0002-6410-1324, Murphy, Robert C and O'Donnell, Valerie B ORCID: https://orcid.org/0000-0003-4089-8460 2017. DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression. Redox Biology 11 , pp. 663-672. 10.1016/j.redox.2017.01.001 |
Lauder, Sarah N., Tyrrell, Victoria J., Allen-Redpath, Keith, Aldrovandi, MacEler, Gray, David, Collins, Peter ORCID: https://orcid.org/0000-0002-6410-1324, Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460 2017. Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo. Wellcome Open Research 2 (1) 10.12688/wellcomeopenres.10308.1 |
Stokes, C. A., Kaur, R., Edwards, M R, Mondhe, Madhav, Robinson, D., Prestwich, E. C., Hume, R. D., Marshall, C. A., Perrie, Y., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Sabroe, I. and Parker, L. C. 2016. Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes. Mucosal Immunology 9 (5) , pp. 1303-1316. 10.1038/mi.2015.137 |
Chiba, Takahito, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Calcutt, M. Wade, Boeglin, William E., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Brash, Alan R. 2016. The precise structures and stereochemistry of trihydroxy-linoleates esterified in human and porcine epidermis and their significance in skin barrier function: Implication of an epoxide hydrolase in the transformations of linoleate. Journal of Biological Chemistry 291 (28) , pp. 14540-14544. 10.1074/jbc.M115.711267 |
Bascoul-Colombo, Cécile, Guschina, Irina A., Maskrey, Benjamin H., Good, Mark ORCID: https://orcid.org/0000-0002-1824-1203, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 2016. Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1861 (6) , pp. 524-537. 10.1016/j.bbalip.2016.03.005 |
Hinz, Christine, Aldrovandi, Maceler, Uhlson, Charis, Marnett, Lawrence J., Longhurst, Hilary J., Warner, Timothy D., Alam, Saydul, Slatter, David A., Lauder, Sarah N., Allen-Redpath, Keith, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2016. Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid. Journal of Biological Chemistry 291 (26) , pp. 13448-13464. 10.1074/jbc.M115.700609 |
Slatter, David A., Aldrovandi, Maceler, O'Connor, Anne ORCID: https://orcid.org/0000-0003-2268-4231, Allen, Stuart M., Brasher, Christopher J., Murphy, Robert C., Mecklemann, Sven, Ravi, Saranya, Darley-Usmar, Victor and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 2016. Mapping the human platelet lipidome reveals cytosolic phospholipase A2 as a regulator of mitochondrial bioenergetics during activation. Cell Metabolism 23 (5) , pp. 930-944. 10.1016/j.cmet.2016.04.001 |
Jones, Victoria, Birrell, Mark, Maher, Sarah, Griffiths, Mark, Grace, Megan, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671 and Belisi, Maria 2016. Role of Ep2 and Ep4 receptors in airway microvascular leak induced by prostaglandin E2. British Journal of Pharmacology 173 (6) , pp. 992-1004. 10.1111/bph.13400 |
Freeman, Phillip, Moschonas, Konstantinos, Hinz, Christine, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Kinnaird, Tim D., James, Philip E. and Anderson, Richard A. 2015. Changes in platelet function independent of pharmacotherapy following coronary intervention in non-ST-elevation myocardial infarction patients. Atherosclerosis 243 (1) , pp. 320-327. 10.1016/j.atherosclerosis.2015.09.024 |
McCully, Michelle L., Collins, Paul J., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Billen, Jaak, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572 2015. Skin metabolites define a new paradigm in the localization of skin tropic memory T cells. Journal of Immunology 195 (1) , pp. 96-104. 10.4049/jimmunol.1402961 |
Percy, Charles L., Hartmann, Rudolf, Jones, Rhidian M., Balachandran, Subramaniam, Mehta, Dheeraj, Dockal, Michael, Scheiflinger, Friedrich, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Hall, Judith Elizabeth ORCID: https://orcid.org/0000-0002-6770-7372 and Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 2015. Correcting thrombin generation ex vivo using different haemostatic agents following cardiac surgery requiring the use of cardiopulmonary bypass. Blood Coagulation and Fibrinolysis 26 (4) , pp. 357-367. 10.1097/MBC.0000000000000243 |
Ravi, Saranya, Chacko, Balu, Sawada, Hirotaka, Kramer, Philip A., Johnson, Michelle S., Benavides, Gloria A., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Marques, Marisa B. and Darley-Usmar, Victor M. 2015. Metabolic plasticity in resting and thrombin activated platelets. PLoS ONE 10 (4) , e0123597. 10.1371/journal.pone.0123597 |
Morgan, Alwena H., Hammond, Victoria J., Sakoh-Nakatogawa, Machiko, Ohsumi, Yoshinori, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Blanchet, Fabien, Piguet, Vincent, Kiselyov, Kirill and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2015. A novel role for 12/15-lipoxygenase in regulating autophagy. Redox Biology 4 , pp. 40-47. 10.1016/j.redox.2014.11.005 |
Friedmann Angeli, Jose Pedro, Schneider, Manuela, Proneth, Bettina, Tyurina, Yulia Y., Tyurin, Vladimir A., Hammond, Victoria J., Herbach, Nadja, Aichler, Michaela, Walch, Axel, Eggenhofer, Elke, Basavarajappa, Devaraj, Rådmark, Olof, Kobayashi, Sho, Seibt, Tobias, Beck, Heike, Neff, Frauke, Esposito, Irene, Wanke, Rüdiger, Förster, Heidi, Yefremova, Olena, Heinrichmeyer, Marc, Bornkamm, Georg W., Geissler, Edward K., Thomas, Stephen B., Stockwell, Brent R., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Kagan, Valerian E., Schick, Joel A. and Conrad, Marcus 2014. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nature Cell Biology 16 , pp. 1180-1191. 10.1038/ncb3064 |
Mathie, S. A., Dixon, K. L., Walker, S. A., Tyrell, Victoria Jayne, Mondhe, M., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Gregory, L. G. and Lloyd, C. M. 2014. Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge. Allergy 70 (1) , pp. 80-89. 10.1111/all.12536 |
O'Donnell, Valerie ORCID: https://orcid.org/0000-0003-4089-8460, Murphy, Robert C. and Watson, Steve P. 2014. Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets. Circulation Research 114 (7) , pp. 1185-1203. 10.1161/CIRCRESAHA.114.301597 |
Aldrovandi, Maceler, Hammond, Victoria Jayne, Podmore, Helen, Hornshaw, Martin, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Marnett, Lawrence J., Slatter, David, Murphy, Robert C., Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2013. Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation. Journal of Lipid Research 54 (11) , pp. 3085-3097. 10.1194/jlr.M041533 |
Pauling, J. D., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Mchugh, N. J. 2013. The contribution of platelets to the pathogenesis of Raynaud's phenomenon and systemic sclerosis. Platelets 24 (7) , pp. 503-515. 10.3109/09537104.2012.719090 |
Bonilla, L., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Rubbo, H. and Trostchansky, A. 2013. Regulation of protein kinase C by nitroarachidonic acid: impact on human platelet activation. Archives of Biochemistry and Biophysics 533 (1-2) , pp. 55-61. 10.1016/j.abb.2013.03.001 |
Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Hammond, Victoria Jayne, Aldrovandi, Maceler, Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Hart, Keith William, Murphy, Robert C., Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2013. Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation. Proceedings of the National Academy of Sciences of the United States of America 110 (15) , pp. 5875-5880. 10.1073/pnas.1222419110 |
Aldrovandi, Maceler and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2013. Oxidized PLs and vascular inflammation. Current Atherosclerosis Reports 15 (5) , pp. 1989-1996. 10.1007/s11883-013-0323-y |
Hammond, Victoria Jayne, Morgan, Alwena H., Lauder, Sarah Nicol, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Brown, Sarah, Freeman, Bruce A., Lloyd, Clare M., Davies, Jane, Bush, Andrew, Levonen, Anna-Liisa, Kansanen, Emilia, Villacorta, Luis, Chen, Y. Eugene, Porter, Ned, Garcia-Diaz, Yoel M., Schopfer, Francisco J. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ. Journal of Biological Chemistry 287 (50) , pp. 41651-41666. 10.1074/jbc.M112.405407 |
Hammond, Victoria Jayne and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Esterified eicosanoids: generation, characterization and function. Biochimica et Biophysica Acta - Biomembranes 1818 (10) , pp. 2403-2412. 10.1016/j.bbamem.2011.12.013 |
Reynolds, Sophie Leanne, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Williams, H., Smale, Shaun, Stephenson, Hayden J., Amos, Nick, George, S. J., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Lang, Derek 2012. Contractile, but not endothelial, dysfunction in early inflammatory arthritis: a possible role for matrix metalloproteinase-9. British Journal of Pharmacology 167 (3) , pp. 505-514. 10.1111/j.1476-5381.2012.01988.x |
O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Murphy, Robert C. 2012. New families of bioactive oxidized phospholipids generated by immune cells: Identification and signaling actions. Blood 120 (10) , pp. 1985-1992. 10.1182/blood-2012-04-402826 |
Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Oxidized phospholipid signaling in immune cells. Current Opinion in Pharmacology 12 (4) , pp. 471-477. 10.1016/j.coph.2012.02.013 |
Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Heydeck, Dagmar, Jones, Gareth Wyn, Kronke, Gerhard, Funk, Colin D., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Adams, Deborah, Kuhn, Hartmut and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Development of myeloproliferative disease in 12/15-lipoxygenase deficiency [Letter]. Blood 119 (25) , pp. 6173-6174. 10.1182/blood-2012-02-410928 |
O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2011. Mass spectrometry analysis of oxidized phosphatidylcholine and phosphatidylethanolamine. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1811 (11) , pp. 818-826. 10.1016/j.bbalip.2011.07.018 |
Ruge, Fiona, Glavini, Aikaterini, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Richards, Hannah E., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Philpott, Michael P. and Porter, Rebecca ORCID: https://orcid.org/0000-0001-6748-0916 2011. Delineating immune-mediated mechanisms underlying hair follicle destruction in the mouse mutant defolliculated. Journal of Investigative Dermatology 131 (3) , pp. 572-579. 10.1038/jid.2010.379 |
Zhao, Jinming, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Balzar, Silvana, St. Croix, Claudette M., Trudeau, John B. and Wenzel, Sally E. 2011. 15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells. Proceedings of the National Academy of Sciences of the United States of America 108 (34) , pp. 14246-14251. 10.1073/pnas.1018075108 |
Trostchansky, A., Bonilla, L., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Marnett, L. J., Radi, R. and Rubbo, H. 2011. Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2. Journal of Biological Chemistry 286 (15) , pp. 12891-12900. 10.1074/jbc.M110.154518 |
Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Morgan, Lloyd T., Maskrey, Ben, Murphy, Robert C., Kuhn, Hartmut, Hazen, Stanley L., Goodall, Alison H., Hamali, Hassan A., Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2010. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. Journal of Biological Chemistry 285 (10) , pp. 6891-6903. 10.1074/jbc.M109.078428 |
Morgan, Alwena Haf, Hammond, Victoria Jayne, Morgan, Lloyd, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Tallman, Keri A., Garcia-Diaz, Yoel Ruslan, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Porter, Ned A., Murphy, Robert C. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2010. Quantitative assays for esterified oxylipins generated by immune cells. Nature Protocols 5 (12) , pp. 1919-1931. 10.1038/nprot.2010.162 |
Ivanov, Igor, Heydeck, Dagmar, Hofheinz, Katharina, Roffeis, Jana, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Kuhn, Hartmut and Walther, Matthias 2010. Molecular enzymology of lipoxygenases. Archives of biochemistry and biophysics 503 (2) , pp. 161-174. 10.1016/j.abb.2010.08.016 |
Morgan, Lloyd T., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Kühn, Hartmut and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2010. Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase. Biochemical Journal 431 (1) , pp. 141-148. 10.1042/BJ20100415 |
Tull, Samantha P., Yates, Clara M., Maskrey, Ben, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Madden, Jackie, Grimble, Robert F., Calder, Philip C., Nash, Gerard B. and Rainger, G. Ed. 2009. Omega-3 fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment. PLoS Biology 7 (8) , e1000177. 10.1371/journal.pbio.1000177 |
Rubbo, Homero, Trostchansky, Andrés and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2009. Peroxynitrite-mediated lipid oxidation and nitration: mechanisms and consequences. Archives of Biochemistry and Biophysics 484 (2) , pp. 167-172. 10.1016/j.abb.2008.11.007 |
Ferreira, Ana M., Ferrari, Mariana I., Trostchansky, Andrés, Batthyany, Carlos, Souza, José M., Alvarez, María N., López, Gloria V., Baker, Paul R. S., Schopfer, Francisco J., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Freeman, Bruce A. and Rubbo, Homero 2009. Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate. Biochemical Journal 417 (1) , pp. 223-234. 10.1042/BJ20080701 |
Maskrey, B. H., Bermudez-Fajardo, A., Morgan, Alwena Haf, Stewart-Jones, Esther, Dioszeghy, Vincent, Taylor, G. W., Baker, P. R. S., Coles, Barbara, Coffey, Marcus Jonathan, Kuhn, H. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2009. Activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase [Addition]. Journal of Biological Chemistry 284 (37) , p. 25460. 10.1074/jbc.A611776200 |
Morgan, Alwena Haf, Dioszeghy, Vincent, Maskrey, Benjamin, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Mathie, Sara A., Lloyd, Clare M., Kuhn, Hartmut, Topley, Nicholas, Coles, Barbara, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2009. Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. Journal of Biological Chemistry 284 (32) , pp. 21185-21191. 10.1074/jbc.M109.021634 |
Baker, Paul R. S., Schopfer, Francisco J., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Freeman, Bruce A. 2009. Convergence of nitric oxide and lipid signaling: anti-inflammatory nitro-fatty acids. Free Radical Biology & Medicine 46 (8) , pp. 989-1003. 10.1016/j.freeradbiomed.2008.11.021 |
Gregory, L. G., Causton, B., Murdoch, J. R., Mathie, S. A., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Priest, F. M., Quint, D. J. and Lloyd, C. M. 2009. Inhaled house dust mite induces pulmonary T helper 2 cytokine production. Clinical and Experimental Allergy 39 (10) , pp. 1597-1610. 10.1111/j.1365-2222.2009.03302.x |
Zhao, Jinming, Maskrey, Ben, Balzar, Silvana, Chibana, Kazuyuki, Mustovich, Anthony, Hu, Haizhen, Trudeau, John B., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Wenzel, Sally E. 2009. Interleukin-13-induced MUC5AC is regulated by 15-Lipoxygenase 1 pathway in human bronchial epithelial cells. American Journal of Respiratory and Critical Care Medicine 179 (9) , pp. 782-790. 10.1164/rccm.200811-1744OC |
Morton, Jonathan, Coles, Barbara, Wright, Kate Louise, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Morrow, Jason D., Terry, Erin S., Anning, Peter, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Dioszeghy, Vincent, Kuhn, Hartmut, Chaitidis, Pavlos, Hobbs, Adrian J., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2008. Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFN -dependent iNOS expression in the vasculature of healthy mice. Blood 111 (10) , pp. 5187-5194. 10.1182/blood-2007-10-117283 |
Dioszeghy, Vincent, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Maskrey, Benjamin H., Colmont, Chantal Sophie, Topley, Nicholas, Chaitidis, Pavlos, Kühn, Hartmut, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2008. 12/15-lipoxygenase regulates the inflammatory response to bacterial products in vivo. The Journal of Immunology 181 (9) , pp. 6514-6524. |
Coles, Barbara, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Rose-John, Stefan, Scheller, J., Jones, S. A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2007. Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo. American Journal of Pathology 171 (1) , pp. 315-325. 10.2353/ajpath.2007.061078 |
Anning, Peter Brian, Coles, Barbara, Morton, Jonathan, Wang, Haibin, Uddin, Jashim, Morrow, Jason D., Dey, Sudhansu K., Marnett, Lawrence J. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2006. Nitric Oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors. Blood 108 (13) , pp. 4059-4062. 10.1182/blood-2006-02-005330 |
Williams, Paula Claire, Coffey, Marcus Jonathan, Coles, Barbara, Sanchez, Stephanie, Morrow, Jason D., Cockcroft, John Ronald, Lewis, Malcolm John and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2005. In vivo aspirin supplementation inhibits nitric oxide consumption by human platelets. Blood 106 (8) , pp. 2737-2743. 10.1182/blood-2005-02-0664 |
Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Anning, Peter Brian, Coffey, Marcus Jonathan, Roberts, Andrew Glyn, Marnett, Lawrence J. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2005. Depletion of iNOS-derived nitric oxide by prostaglandin H synthase-2 in inflammation-activated J774.2 macrophages through lipohydroperoxidase turnover. Biochemical Journal 385 (3) , pp. 815-821. 10.1042/BJ20041353 |
Coffey, Marcus Jonathan, Coles, Barbara, Locke, Matthew, Bermudez-Fajardo, Alexandra, Williams, Paula Claire, Jarvis, Gavin E. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2004. Interactions of 12-lipoxygenase with phospholipase A2 isoforms following platelet activation through the glycoprotein VI collagen receptor. FEBS Letters 576 (1-2) , pp. 165-168. 10.1016/j.febslet.2004.09.007 |
Coffey, Marcus Jonathan, Jarvis, Gavin E, Gibbins, Jonathan M., Coles, Barbara, Barrett, Natasha E., Wylie, Oliver R.E. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2004. Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis. Circulation Research 94 (12) , pp. 1598-1605. 10.1161/01.RES.0000132281.78948.65 |
Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Coffey, Marcus Jonathan, McLean, Rhona Murray, Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324, Lewis, Malcolm John, Cross, Andrew R. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2002. Characterization of nitric oxide consumption pathways by normal, chronic granulomatous disease and myeloperoxidase-deficient human neutrophils. The Journal of Immunology 169 (10) , pp. 5889-5896. |
Coles, Barbara, Bloodsworth, Allison, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Lewis, Malcolm John, Cross, Andrew R., Freeman, Bruce A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2002. Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells. Circulation Research 91 (5) , pp. 375-381. 10.1161/01.RES.0000032114.68919.EF |
Coffey, Marcus Jonathan, Natarajan, Rama, Chumley, Philip H., Coles, Barbara, Thimmalapura, Pushpa-Rekha, Nowell, Mari Ann, Kühn, Hartmut, Lewis, Malcolm John, Freeman, Bruce A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2001. Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 98 (14) , pp. 8006-8011. 10.1073/pnas.141136098 |