Twine, Christopher P.  ORCID: https://orcid.org/0000-0003-0385-5760, Ahmed, Haroon ORCID: https://orcid.org/0000-0002-0634-8548, Lugg-Widger, Fiona V. ORCID: https://orcid.org/0000-0003-0029-9703, Waldron, Cherry-Ann ORCID: https://orcid.org/0000-0001-8465-2492, Bown, Matt J. and Sydes, Matthew R.
2024.
Challenges of using routinely collected healthcare system data in randomised trials.
European Journal of Vascular and Endovascular Surgery
68
(3)
, pp. 416-417.
10.1016/j.ejvs.2024.05.010
|
Preview |
PDF
- Accepted Post-Print Version
Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (194kB) | Preview |
Official URL: http://dx.doi.org/10.1016/j.ejvs.2024.05.010
Abstract
There is increasing interest in using individually linked, routinely collected healthcare systems data for randomised controlled trials (RCTs). These data enabled trials aim to reduce site and participant burden and increase efficiency of trial delivery.1 Routinely collected data have successfully been used in large big data retrospective studies for years,2 and new methodology such as target trial emulation has enabled researchers to reduce the bias inherent to retrospective data.3 This still cannot replace the traditional randomised trial design, but a hybrid approach potentially builds on the strengths of both designs.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Medicine Research Institutes & Centres > Centre for Trials Research (CNTRR) |
| Publisher: | Elsevier |
| ISSN: | 1078-5884 |
| Date of First Compliant Deposit: | 30 August 2024 |
| Date of Acceptance: | 10 May 2024 |
| Last Modified: | 10 May 2025 01:45 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/171680 |
Actions (repository staff only)
 |
Edit Item |
Dimensions
Dimensions