Effects of incorporation of nano-fluorapatite particles on microhardness, fluoride releasing properties, and biocompatibility of a conventional glass ionomer cement (GIC)

Moshaverinia, Maryam, Borzabadi Farahani, Ali, Sameni, Abdi, Moshaverinia, Alireza and Ansari, Sahar 2016. Effects of incorporation of nano-fluorapatite particles on microhardness, fluoride releasing properties, and biocompatibility of a conventional glass ionomer cement (GIC). Dental Materials Journal 35 (5) , pp. 817-821. 10.4012/dmj.2015-437

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Abstract

Present study evaluated effects of addition of Nanoparticles fluorapatite (Nano-FA) on microhardness and fluoride release of a Glass Ionomer Cement (GIC, Fuji IX GP Fast). Forty-eight specimens prepared, divided equally into 4 groups (2 with Nano-FA); after 24 h and one week Vickers microhardness (HV) was measured. Nano-FA specimens were made from addition of nano-FA to Fuji IX powder (glass powder/Nano-FA ratio=20:1 wt/wt, 3.6:1 P/L ratio). At 24 h, mean (95% CI) HV for GIC and Nano-FA GIC were 40.59 (39.51–41.66) and 46.89 (45.95–47.82) kg/mm2, and at one week 44.98 (44.23–45.72), 53.29 (52.58–53.99) kg/mm2, respectively. Findings indicated higher HV in Nano-FA specimens (F=221.088, p<0.001). Twenty-eight days weekly cumulative fluoride release in both groups was not different (p>0.05). MTT assay exhibited no inhibition of cell proliferation or reduction in metabolic activity in experimental [84.0 (3.3)] or control groups [85.1 (4.7)] with no difference between groups (p>0.05). New nano-FA GIC was biocompatible and showed improved surface hardness. Future clinical trials can verify the usefulness of Nano-FA GIC.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Dentistry
Publisher:	The Japanese Society for Dental Materials and Devices
ISSN:	0287-4547
Date of Acceptance:	22 June 2016
Last Modified:	08 Nov 2024 11:16
URI:	https://orca.cardiff.ac.uk/id/eprint/172457

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