Melchor, Lorenzo and Smalley, Matthew John ![]() |
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Abstract
In recent years, the mammary gland epithelium has been shown to be a mixture of differentiated cell populations in a hierarchical relationship with their stem and progenitor cells. However, the mechanisms that regulate their cellular differentiation processes are still unclear. The identification of genes that govern stem and progenitor cell expansion, or that determine daughter cell fate, will be of crucial interest for understanding breast cancer diversity and, ultimately, improving treatment. Two recent analyses have identified some of the key genes that regulate these processes, lighting up the highway to normal mammary gland development.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Biosciences European Cancer Stem Cell Research Institute (ECSCRI) |
Subjects: | Q Science > Q Science (General) R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
Publisher: | BioMed Central |
ISSN: | 1465-5411 |
Date of First Compliant Deposit: | 30 March 2016 |
Last Modified: | 29 Jun 2023 08:34 |
URI: | https://orca.cardiff.ac.uk/id/eprint/24745 |
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