Browse by Current Cardiff authors

Williams, Jason S., Higgins, Adam T. ORCID: https://orcid.org/0000-0002-2906-8151, Stott, Katie J., Thomas, Carly, Farrell, Lydia, Bonnet, Cleo, Peneva, Severena, Derrick, Anna V., Hay, Trevor, Wang, Tianqi, Morgan, Claire, Dwyer, Sarah, D'Ambrogio, Joshua, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Dyson, Paul 2024. Enhanced bacterial cancer therapy delivering therapeutic RNA interference of c-Myc. Cell & Bioscience 14 (38) 10.1186/s13578-024-01206-8

Tornillo, Giusy, Warrington, Lauren, Kendrick, Howard, Higgins, Adam T. ORCID: https://orcid.org/0000-0002-2906-8151, Hay, Trevor, Beck, Sam and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2024. Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model. Disease Models and Mechanisms 17 (1) , dmm050211. 10.1242/dmm.050211

Varney, Danielle, O'Neill, Dan, O'Neill, Maeve, Church, David, Stell, Anneliese, Beck, Sam, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Brodbelt, David 2023. Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016. Veterinary Record 193 (5) , e3054. 10.1002/vetr.3054

Ordonez, Liliana, Tornillo, Giusy, Kendrick, Howard, Hay, Trevor and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2023. NOTCH and AKT signalling interact to drive mammary tumour heterogeneity. Cancers 15 (17) , 4324. 10.3390/cancers15174324

O'Neill, Dan, Edmunds, Grace, Urquhart-Gilmore, Jade, Church, David, Rutherford, Lynda, Smalley, Matthew ORCID: https://orcid.org/0000-0001-9540-1146 and Brodbelt, David 2023. Dog breeds and conformations predisposed to osteosarcoma in the UK: a VetCompass study. Canine Medicine and Genetics 10 , 8. 10.1186/s40575-023-00131-2

Edmunds, Grace, Beck, Sam, Umakant Kale, Kedar, Spasic, Irena ORCID: https://orcid.org/0000-0002-8132-3885, O'Neill, Dan, Brodbelt, David and Smalley, Matthew J ORCID: https://orcid.org/0000-0001-9540-1146 2023. Associations between dog breed and clinical features of mammary epithelial neoplasia in bitches: an epidemiological study of submissions to a single diagnostic pathology centre between 2008-2021. Journal of Mammary Gland Biology and Neoplasia 28 (6) 10.1007/s10911-023-09531-3

Shorning, Boris, Trent, Neil, Griffiths, David F., Worzfeld, Thomas, Offermanns, Stefan, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Williamson, Magali 2023. Plexin-B1 mutation drives metastasis in prostate cancer mouse models. Cancer Research Communications 3 (3) , pp. 444-458. 10.1158/2767-9764.CRC-22-0480

Dimitriou, Pantelitsa, Li, Jin ORCID: https://orcid.org/0000-0002-4672-6806, Tornillo, Giusy, Smalley, Matthew ORCID: https://orcid.org/0000-0001-9540-1146 and Barrow, David ORCID: https://orcid.org/0000-0003-2096-7262 2022. Droplet incubator: a new droplet-based model to investigate living cell-synthetic cell interactions. Presented at: MicroTAS 2022, Hangzhou, China, 23-27 October 2022.

Castro, Jessica, Tornillo, Giusy, Ceada, Gerardo, Ramos-Neble, Beatriz, Bravo, Marlon, Ribo', Marc, Vilanova, Maria, Smalley, Matthew ORCID: https://orcid.org/0000-0001-9540-1146 and Benito, Antoni 2021. A nuclear-directed ribonuclease variant targets cancer stem cells and inhibits migration and invasion of breast cancer cells. Cancers 13 (17) , 4350. 10.3390/cancers13174350

Ordonez, Liliana D., Melchor, Lorenzo, Greenow, Kirsty R., Kendrick, Howard, Tornillo, Giusy, Bradford, James, Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854 and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2021. Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model. Disease Models and Mechanisms 14 (5) , dmm048736. 10.1242/dmm.048736

Edmunds, Grace L., Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Beck, Sam, Errington, Rachel J. ORCID: https://orcid.org/0000-0002-8016-4376, Gould, Sara, Winter, Helen, Brodbelt, David and O'Neill, Dan 2021. Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study. Canine Medicine and Genetics 8 , 2. 10.1186/s40575-021-00100-7

Pires, Ana, Greenshields Watson, Alexander, Jones, Emma, Smart, Kathryn, Lauder, Sarah N., Somerville, Michelle, Milutinovic, Stefan ORCID: https://orcid.org/0000-0002-3163-3383, Kendrick, Howard, Hindley, James P., French, Rhiannon, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Watkins, William John ORCID: https://orcid.org/0000-0003-3262-6588, Andrews, Robert, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2020. Immune remodelling of the extracellular matrix drives loss of cancer stem cells and tumor rejection. Cancer Immunology Research 8 (12) , 1520 - 1531. 10.1158/2326-6066.CIR-20-0070

Regan, Joseph L and Smalley, Matthew J ORCID: https://orcid.org/0000-0001-9540-1146 2020. Integrating single-cell RNA-sequencing and functional assays to decipher mammary cell states and lineage hierarchies. NPJ Breast Cancer 6 , 32. 10.1038/s41523-020-00175-8

Shorning, Boris Y., Dass, Manisha S., Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2020. The PI3K-AKT-mTOR pathway and prostate cancer: at the crossroads of AR, MAPK, and WNT signaling. International Journal of Molecular Sciences 21 (12) , 4507. 10.3390/ijms21124507

Ordonez, Liliana D, Hay, Trevor, McEwen, Robert, Polanska, Urszula M, Hughes, Adina, Delpuech, Oona, Cadogan, Elaine, Powell, Steve, Dry, Jonathan, Tornillo, Giusy, Silcock, Lucy, Leo, Elisabetta, O'Connor, Mark J, Clarke, Alan R ORCID: https://orcid.org/0000-0002-4281-426X and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2019. Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours. Oncotarget 10 (27) , pp. 2586-2606. 10.18632/oncotarget.26830

Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2019. APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression. BMC Cancer 19 , 677. 10.1186/s12885-019-5867-y

Tornillo, Giusy, Knowlson, Catherine, Kendrick, Howard, Cooke, Joe, Mirza, Hasan, Aurrekoetxea-Rodriguez, Iskander, d.M. Vivanco, Maria, Buckley, Niamh E., Grigoriadis, Anita and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2018. Dual mechanisms of LYN kinase dysregulation drive aggressive behaviour in breast cancer cells. Cell Reports 25 (13) , pp. 3674-3692. 10.1016/j.celrep.2018.11.103

Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Li, Jason, Meniel, Valerie S., Fennell, Christina M., Waring, Paul, Montgomery, Karen G., Rebello, Richard J., Macpherson, Arthi A., Koushyar, Sarah, Furic, Luc, Cullinane, Carleen, Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Simpson, Kaylene J., Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Shepherd, Peter R., Humbert, Patrick O., Sansom, Owen J. and Phillips, Wayne A. 2018. Identification of Pik3ca mutation as a genetic driver of prostate cancer that cooperates with Pten loss to accelerate progression and castration-resistant growth. Cancer Discovery 8 (6) , pp. 764-779. 10.1158/2159-8290.CD-17-0867

Jefferies, Matthew T., Cox, Adam C., Shorning, Boris Y., Meniel, Valerie, Griffiths, David, Kynaston, Howard G. ORCID: https://orcid.org/0000-0003-1902-9930, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. 2017. PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis. Journal of Pathology 243 (4) , pp. 442-456. 10.1002/path.4977

Chiang, Kelly, Zielinska, Agnieszka E., Shaaban, Abeer M., Sanchez-Bailon, Maria Pilar, Jarrold, James, Clarke, Thomas L, Zhang, Jingxian, Francis, Adele, Jones, Louise J., Smith, Sally, Barbash, Olena, Guccione, Ernesto, Farnie, Gillian, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Davies, Clare C. 2017. PRMT5 is a critical regulator of breast cancer stem cell function via Histone Methylation and FOXP1 expression. Cell Reports 21 (12) , pp. 3498-3513. 10.1016/j.celrep.2017.11.096

Soady, Kelly J., Tornillo, Giusy, Kendrick, Howard, Meniel, Valerie, Olijnyk-Dallis, Daria, Morris, Joanna S., Stein, Torstein, Gusterson, Barry A., Isacke, Clare M. and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2017. Receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis. Development 144 (20) , pp. 3777-3788. 10.1242/dev.149120

Jardé, Thierry, Lloyd-Lewis, Bethan, Thomas, Mairian, Kendrick, Howard, Melchor, Lorenzo, Bougaret, Lauriane, Watson, Peter D., Ewan, Kenneth ORCID: https://orcid.org/0000-0001-6622-9009, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963 2016. Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids. Nature Communications 7 , 13207. 10.1038/ncomms13207

Abraham, Thomas, Barbier, Michaël, Jaensch, Steffen, Cornelissen, Frans, Vidic, Suzana, Gjerde, Kjersti, de Hoogt, Ronald, Graeser, Ralph, Gustin, Emmanuel, Chong, Yolanda T. and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2016. Ellipsoid segmentation model for analyzing light-attenuated 3D confocal image stacks of fluorescent multi-cellular spheroids. PLoS ONE 11 (6) , e0156942. 10.1371/journal.pone.0156942

Estrada, Marta F., Rebelo, Sofia P., Davies, Emma J., Pinto, Marta T., Pereira, Hugo, Santo, Vítor E., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Barry, Simon T., Gualda, Emilio J., Alves, Paula M., Anderson, Elizabeth and Brito, Catarina 2016. Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression. Biomaterials 78 , pp. 50-61. 10.1016/j.biomaterials.2015.11.030

Ferrari, Nicola, Riggio, Alessandra I., Mason, Susan, McDonald, Laura, King, Ayala, Higgins, Theresa, Rosewell, Ian, Neil, James C., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Sansom, Owen J., Morris, Joanna, Cameron, Ewan R. and Blyth, Karen 2015. Runx2 contributes to the regenerative potential of the mammary epithelium. Scientific Reports 5 , 15658. 10.1038/srep15658

Greenow, Kirsty Rhian and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2015. Overview of genetically engineered mouse models of breast cancer used in translational biology and drug development. Current Protocols in Pharmacology 70 (1) , 70:14.36.1-14.36.14.. 10.1002/0471141755.ph1436s70

Tornillo, Giusy and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2015. ERrrr...Where are the progenitors? Hormone receptors and mammary cell heterogeneity. Journal of Mammary Gland Biology and Neoplasia 20 (1) , pp. 63-73. 10.1007/s10911-015-9336-1

Francis, Jeffrey C., Melchor, Lorenzo, Campbell, James, Kendrick, Howard, Wei, Wenbin, Armisen-Garrido, Javier, Assiotis, Ioannis, Chen, Lina, Kozarewa, Iwanka, Fenwick, Kerry, Swain, Amanda, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Lord, Christopher J. and Ashworth, Alan 2015. Whole exome DNA sequence analysis of Brca2 and Trp53 deficient mouse mammary gland tumours. Journal of Pathology 236 (2) , pp. 186-200. 10.1002/path.4517

Iglesias, Juan Manuel, Cairney, Claire J., Ferrier, Roderick K., McDonald, Laura, Soady, Kelly, Kendrick, Howard, Pringle, Marie-Anne, Morgan, Reginald O., Martin, Finian, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Blyth, Karen and Stein, Torsten 2015. Annexin A8 identifies a subpopulation of transiently quiescent c-Kit positive luminal progenitor cells of the ductal mammary epithelium. Plos One 10 (3) , e0119718. 10.1371/journal.pone.0119718

Soady, Kelly J., Kendrick, Howard, Gao, Qiong, Tutt, Andrew, Zvelebil, Marketa, Ordonez, Liliana D., Quist, Jelmar, Tan, David Wei-Min, Isacke, Clare M., Grigoriadis, Anita and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2015. Mouse mammary stem cells express prognostic markers for triple-negative breast cancer. Breast Cancer Research 17 , 31. 10.1186/s13058-015-0539-6

Hickman, John A., Graeser, Ralph, de Hoogt, Ronald, Vidic, Suzana, Brito, Catarina, Gutekunst, Matthias, van der Kuip, Heiko, consortium, IMI PREDECT and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2014. Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo. Biotechnology Journal 9 (9) , pp. 1115-1128. 10.1002/biot.201300492

Melchor, Lorenzo, Molyneux, Gemma, Mackay, Alan, Magnay, Fiona-Ann, Atienza, María, Kendrick, Howard, Nava-Rodrigues, Daniel, López-García, María Ángeles, Milanezi, Fernanda, Greenow, Kirsty, Robertson, David, Palacios, José, Reis-Filho, Jorge S. and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2014. Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models. Journal of Pathology 233 (2) , pp. 124-137. 10.1002/path.4345

Cowley, Michael, Garfield, Alastair S., Madon-Simon, Marta, Charalambous, Marika, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Kendrick, Howard, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Parry, Aled J., Carney, Sara, Oakey, Rebecca J., Heisler, Lora K., Moorwood, Kim, Wolf, Jason B. and Ward, Andrew 2014. Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup. PLoS Biology 12 (2) , e1001799. 10.1371/journal.pbio.1001799

Regan, Joseph L., Sourisseau, Tony, Soady, Kelly, Kendrick, Howard, McCarthy, Afshan, Tang, Chan, Brennan, Keith, Linardopoulos, Spiros, White, Donald E. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2013. Aurora A kinase regulates mammary epithelial cell fate by determining mitotic spindle orientation in a Notch-dependent manner. Cell Reports 4 (1) , pp. 110-123. 10.1016/j.celrep.2013.05.044

Gastaldi, S., Sassi, F., Accornero, P., Torti, D., Galimi, F., Migliardi, G., Molyneux, G., Perera, T., Comoglio, P. M., Boccaccio, C, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Bertotti, A. and Trusolino, L. 2013. Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer. Oncogene 32 , pp. 1428-1440. 10.1038/onc.2012.154

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Piggott, Luke and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2013. Breast cancer stem cells: obstacles to therapy. Cancer Letters 338 (1) , pp. 57-62. 10.1016/j.canlet.2012.04.023

Zvelebil, Marketa, Oliemuller, Erik, Gao, Qiong, Wansbury, Olivia, Mackay, Alan, Kendrick, Howard, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Reis-Filho, Jorge S. and Howard, Beatrice A. 2013. Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers. Breast Cancer Research 15 (2) , R25. 10.1186/bcr3403

Eccles, Suzanne A., Aboagye, Eric O., Ali, Simak, Anderson, Annie S., Armes, Jo, Berditchevski, Fedor, Blaydes, Jeremy P., Brennan, Keith, Brown, Nicola J., Bryant, Helen E., Bundred, Nigel J., Burchell, Joy M., Campbell, Anna M., Carroll, Jason S., Clarke, Robert B., Coles, Charlotte E., Cook, Gary J. R., Cox, Angela, Curtin, Nicola J., Dekker, Lodewijk V., dos Santos Silva, Isabel, Duffy, Stephen W., Easton, Douglas F., Eccles, Diana M., Edwards, Dylan R., Edwards, Joanne, Evans, D. Gareth, Fenlon, Deborah F., Flanagan, James M., Foster, Claire, Gallagher, William M., Garcia-Closas, Montserrat, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Gescher, Andy J., Goh, Vicky, Groves, Ashley M., Harvey, Amanda J., Harvie, Michelle, Hennessy, Bryan T., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Holen, Ingunn, Howell, Sacha J., Howell, Anthony, Hubbard, Gill, Hulbert-Williams, Nick, Hunter, Myra S., Jasani, Bharat, Jones, Louise J., Key, Timothy J., Kirwan, Cliona C., Kong, Anthony, Kunkler, Ian H., Langdon, Simon P., Leach, Martin O., Mann, David J., Marshall, John F., Martin, Lesley, Martin, Stewart G., Macdougall, Jennifer E., Miles, David W., Miller, William R., Morris, Joanna R., Moss, Sue M., Mullan, Paul, Natrajan, Rachel, O'Connor, James P. B., O'Connor, Rosemary, Palmieri, Carlo, Pharoah, Paul D. P., Rakha, Emad A., Reed, Elizabeth, Robinson, Simon P., Sahai, Erik, Saxton, John M., Schmid, Peter, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Speirs, Valerie, Stein, Robert, Stingl, John, Streuli, Charles H., Tutt, Andrew N. J., Velikova, Galina, Walker, Rosemary A., Watson, Christine J., Williams, Kaye J., Young, Leonie S. and Thompson, Alastair M. 2013. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Research 15 (5) , R92. 10.1186/bcr3493

Ordonez, Liliana and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2012. Who do they think they are? Wnt-responsive cells reveal their family trees. Breast Cancer Research 14 (6) , 327. 10.1186/bcr3351

Soady, Kelly and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2012. Slugging their way to immortality: Driving mammary epithelial cells into a stem cell-like state. Breast Cancer Research 14 (5) , 319. 10.1186/bcr3188

Hopkins, S., Linderoth, E., Hantschel, O., Suarez-Henriques, P., Pilia, G., Kendrick, Howard, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Superti-Furga, G. and Ferby, I. 2012. Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis. Developmental Cell 23 (3) , pp. 547-559. 10.1016/j.devcel.2012.08.001

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Kendrick, Howard, Sheridan, Julie M., Regan, Joseph L., Prater, Michael D., Lindeman, Geoffrey J., Watson, Christine J., Visvader, Jane E. and Stingl, John 2012. Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods. Journal of Mammary Gland Biology and Neoplasia 17 (2) , pp. 91-97. 10.1007/s10911-012-9257-1

Regan, J. L., Kendrick, Howard, Magnay, F.-A., Vafaizadeh, V., Groner, B. and Smalley, Matthew ORCID: https://orcid.org/0000-0001-9540-1146 2012. c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer. Oncogene 31 (7) , pp. 869-883. 10.1038/onc.2011.289

Milani, E. S., Brinkhaus, H., Dueggeli, R., Klebba, I., Mueller, U., Stadler, M., Kohler, H., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Bentires-Alj, M. 2012. Protein tyrosine phosphatase 1B restrains mammary alveologenesis and secretory differentiation. Development 140 (1) , pp. 117-125. 10.1242/dev.082941

Wansbury, Olivia, Mackay, Alan, Kogata, Naoko, Mitsopoulos, Costas, Kendrick, Howard, Davidson, Kathryn, Ruhrberg, Christiana, Reis- Filho, Jorge, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Zvelebil, Marketa and Howard, Beatrice 2011. Transcriptome analysis of embryonic mammary cells reveals insights into mammary lineage establishment. Breast Cancer Research 13 (4) , R79. 10.1186/bcr2928

Molyneux, Gemma and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2011. The cell of origin of BRCA1 mutation-associated breast cancer: a cautionary tale of gene expression profiling. Journal of Mammary Gland Biology and Neoplasia 16 (1) , pp. 51-55. 10.1007/s10911-011-9202-8

Molyneux, Gemma, Geyer, Felipe, Magnay, Fiona-Ann, McCarthy, Afshan, Kendrick, Howard, Natrajan, Rachael, MacKay, Alan, Grigoriadis, Anita, Tutt, Andrew, Ashworth, Alan, Reis-Filho, Jorge and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2010. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 7 (3) , pp. 403-417. 10.1016/j.stem.2010.07.010

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2010. Isolation, culture and analysis of mouse mammary epithelial cells. Ward, Andrew and Tosh, David, eds. Mouse cell culture : methods and protocols, Methods in Molecular Biology, vol. 633. New York: Springer-Verlag, pp. 139-170. (10.1007/978-1-59745-019-5_11)

Evers, Bastiaan, Speksnijder, Ewoud N., Schut, Eva, Ciampricotti, Metamia, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Derksen, Patrick W. B., Jonkers, Jos and de Visser, Karin E. 2010. A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis. Journal of Pathology 220 (1) , pp. 34-44. 10.1002/path.2655

Bentires-Alj, Mohamed, Clarke, Robert B., Jonkers, Jos, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Stein, Torsten 2009. It's all in the details: methods in breast development and cancer [Meeting Report]. Breast Cancer Research 11 (4) , 305. 10.1186/bcr2346

Grigoriadis, Anita, Oliver, Gavin, Tanney, Austin, Kendrick, Howard, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Jat, Parmjit and Neville, A. Munro 2009. Identification of differentially expressed sense and antisense transcript pairs in breast epithelial tissues. BMC Genomics 10 (1) , 324. 10.1186/1471-2164-10-324

Alexander, Caroline M., Puchalski, Joel, Klos, Kristine S., Badders, Nisha, Ailles, Laurie, Kim, Carla F., Dirks, Peter and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2009. Separating stem cells by flow cytometry: reducing variability for solid tissues. Cell Stem Cell 5 (6) , pp. 579-583. 10.1016/j.stem.2009.11.008

Huser, C. A., Pringle, M. A., Heath, V. J., Bell, A. K., Kendrick, Howard, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Crighton, D., Ryan, K. M., Gusterson, B. A. and Stein, T. 2009. TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival. Cell Death and Differentiation 17 (2) , pp. 304-315. 10.1038/cdd.2009.126

Britt, Kara L., Kendrick, Howard, Regan, Joseph L., Molyneux, Gemma, Magnay, Fiona-Ann, Ashworth, Alan and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2009. Pregnancy in the mature adult mouse does not alter the proportion of mammary epithelial stem/progenitor cells. Breast Cancer Research 11 (2) , R20. 10.1186/bcr2245

Kendrick, Howard, Regan, Joseph, Magnay, Fiona-Ann, Grigoriadis, Anita, Mitsopoulos, Costas, Zvelebil, Marketa and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2008. Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate. BMC Genomics 9 (1) , 591. 10.1186/1471-2164-9-591

Melchor, Lorenzo and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2008. Highway to heaven: mammary gland development and differentiation. Breast Cancer Research 10 (5) , pp. 305-307. 10.1186/bcr2147

Lindeman, Geoffrey, Visvader, Jane, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Eaves, Connie 2008. The future of mammary stem cell biology: the power of in vivo transplants [Letter]. Breast Cancer Research 10 (3) , p. 402. 10.1186/bcr1986

Cariati, Massimiliano, Naderi, Ali, Brown, John P., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Pinder, Sarah E., Caldas, Carlos and Purushotham, Anand D. 2008. Alpha-6 integrin is necessary for the tumourigenicity of a stem cell-like subpopulation within the MCF7 breast cancer cell line. International Journal of Cancer 122 (2) , pp. 298-304. 10.1002/ijc.23103

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Reis-Filho, Jorge and Ashworth, Alan 2008. BRCA1 and stem cells: tumour typecasting. Nature Cell Biology 10 (4) , pp. 377-379. 10.1038/ncb0408-377

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Iravani, M., Leao, M., Grigoriadis, A., Kendrick, Howard, Dexter, T., Fenwick, K., Regan, J. L., Britt, K., McDonald, S., Lord, C. J., Mackay, A. and Ashworth, A. 2007. Regulator of G-protein signalling 2 (RGS2) mRNA is differentially expressed in mammary epithelial subpopulations and overexpressed in the majority of breast cancers. Breast Cancer Research 9 (6) , R85. 10.1186/bcr1834

Molyneux, G., Regan, J. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2007. Common molecular mechanisms of mammary gland development and breast cancer. Cellular and Molecular Life Sciences 64 (24) , pp. 3248-3260. 10.1007/s00018-007-7391-5

Britt, K., Ashworth, A. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2007. Pregnancy and the risk of breast cancer. Endocrine-Related Cancer 14 (4) , pp. 907-933. 10.1677/ERC-07-0137

Sleeman, K. E., Kendrick, H., Robertson, D., Isacke, C. M., Ashworth, A. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2007. Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. Journal of cell biology 176 (1) , pp. 19-26. 10.1083/jcb.200604065

Regan, Joseph and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2007. Prospective isolation and functional analysis of stem and differentiated cells from the mouse mammary gland. Stem Cell Reviews 3 (2) , pp. 124-136. 10.1007/s12015-007-0017-3

Sleeman, Katherine E., Kendrick, Howard, Ashworth, Alan, Isacke, Clare M. and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2006. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Research 8 (R7) 10.1186/bcr1371

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Signoret, Nathalie, Robertson, David, Tilley, Alan, Hann, Anthony, Ewan, Kenneth ORCID: https://orcid.org/0000-0001-6622-9009, Ding, Yanning, Paterson, Hugh and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2005. Dishevelled (Dvl-2) activates canonical Wnt signalling in the absence of cytoplasmic puncta. Journal of Cell Science 118 (22) , pp. 5279-5289. 10.1242/jcs.02647

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Titley, I. and Ashworth, A. 2005. An improved definition of mouse mammary epithelial side population cells. Cytotherapy 7 (6) , pp. 497-508. 10.1080/14653240500361145

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Robert B. 2005. The mammary gland “side population”: a putative stem/progenitor cell marker? Journal of Mammary Gland Biology and Neoplasia 10 (1) , pp. 37-47. 10.1007/s10911-005-2539-0

Ciani, L., Krylova, O., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Salinas, P. 2004. A divergent canonical WNT-signaling pathway regulates microtubule dynamics: Dishevelled signals locally to stabilize microtubules. Journal of Cell Biology 164 (2) , pp. 243-253. 10.1083/jcb.200309096

Alvi, Azra J., Clayton, Helen, Joshi, Chirag, Enver, Tariq, Ashworth, Alan, Vivanco, Maria d. M, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2003. Functional and molecular characterisation of mammary side population cells. Breast Cancer Research 5 (1) , R1-R8. 10.1186/bcr547

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Ashworth, Alan 2003. Stem cells and breast cancer: A field in transit. Nature Reviews Cancer 3 , pp. 832-844. 10.1038/nrc1212

Fraser, Elizabeth, Young, N., Dajani, R., Franca-Koh, J., Ryves, William Jonathan, Williams, R. S. B., Yeo, M., Webster, M.-T., Richardson, C., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Pearl, L. H., Harwood, Adrian John ORCID: https://orcid.org/0000-0003-3124-5169 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2002. Identification of the Axin and Frat binding region of glycogen synthase kinase-3. Journal of Biological Chemistry 277 (3) , pp. 2176-2185. 10.1074/jbc.M109462200

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2001. Wnt signaling and mammary tumorigenesis. Journal of Mammary Gland Biology and Neoplasia 6 (1) , pp. 37-52.

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Leiper, K., Tootle, R., McCloskey, P., O'Hare, M. J. and Hodgson, H. 2001. Immortalisation of human hepatocytes by temperature-sensitive SV40 large-T antigen. In Vitro Cellular and Developmental Biology - Animal 37 (3) , pp. 166-168. 10.1290/1071-2690(2001)037<0166:IOHHBT>2.0.CO;2

Webster, M. T., Rozycka, M., Sara, Elizabeth, Davis, E., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Young, N., Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Wooster, R. 2000. Sequence variants of the Axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding. Genes Chromosomes and Cancer 28 (4) , pp. 443-453. 10.1002/1098-2264(200008)28:4<443::AID-GCC10>3.0.CO;2-D

Naylor, S., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Robertson, D., Gusterson, B. A., Edwards, P. A. and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2000. Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium. Journal of Cell Science 113 (12) , pp. 2129-2138.

Sarkar, L., Cobourne, M., Naylor, S., Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 and Sharpe, P. T. 2000. Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development. Proceedings of the National Academy of Sciences of the United States of America 97 (9) , pp. 4520-4524. 10.1073/pnas.97.9.4520

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Titley, J., Paterson, H., Perusinghe, N., Clarke, C. and O'Hare, M. J. 1999. Differentiation of separated mouse mammary luminal epithelial and myoepithelial cells cultured on EHS matrix analyzed by indirect immunofluorescence of cytoskeletal antigens. Journal of Histochemistry & Cytochemistry 47 (12) , pp. 1513-1524. 10.1177/002215549904701203

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 1999. Wnt signalling in mammalian development and cancer. Cancer and Metastasis Reviews 18 (2) , pp. 215-230. 10.1023/A:1006369223282

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Fraser, Elizabeth, Paterson, Hugh, Naylor, Stuart, Cook, David, Jayatilake, Hiran, Fryer, Lee G., Hutchinson, Lisa, Fry, Michael J. and Dale, Trevor C. 1999. Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription. EMBO Journal 18 (10) , pp. 2823-2835. 10.1093/emboj/18.10.2823

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Leiper, K., Floyd, D., Mobberley, M., Ryder, T., Selden, C., Roberts, Eve A. and Hodgson, H. 1999. Behavior of a cell line derived from normal human hepatocytes on non-physiological and physiological-type substrates: Evidence for enhancement of secretion of liver-specific proteins by a three-dimensional growth pattern. In Vitro Cellular and Developmental Biology - Animal 35 (1) , pp. 22-32. 10.1007/s11626-999-0040-6

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Titley, J. and O'Hare, M. J. 1998. Clonal characterization of mouse mammary luminal epithelial and myoepithelial cells separated by fluorescence-activated cell sorting. In Vitro Cellular and Developmental Biology - Animal 34 (9) , pp. 711-721. 10.1007/s11626-998-0067-0