Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Assessment of DNA complexation onto polyelectrolyte-coated magnetic silica nanoparticles

Dávila-Ibáñez, Ana B., Buurma, Niklaas Jan and Salgueiriño, Verónica 2013. Assessment of DNA complexation onto polyelectrolyte-coated magnetic silica nanoparticles. Nanoscale 5 (11) , pp. 4797-4807. 10.1039/c3nr34358h

Full text not available from this repository.


The polyelectrolyte–DNA complexation method to form magnetoplexes using silica-coated iron oxide magnetic nanoparticles as inorganic substrates is an attractive and promising process in view of the potential applications including magnetofection, DNA extraction and purification, and directed assembly of nanostructures. Herein, we present a systematic physico-chemical study that provides clear evidence of the type of interactions established, reflects the importance of the DNA length, the nanoparticle size and the ionic strength, and permits the identification of the parameters controlling both the stability and the type of magnetoplexes formed. This information can be used to develop targeted systems with properties optimized for the various proposed applications of magnetoplexes.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: RSC Publishing
ISSN: 2040-3364
Last Modified: 04 Jun 2017 05:00

Citation Data

Cited 11 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item