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Schizophrenia genetics: dysbindin under the microscope

Benson, Matthew A., Sillitoe, Roy V. and Blake, Derek J 2004. Schizophrenia genetics: dysbindin under the microscope. Trends in Neurosciences 27 (9) , pp. 516-519. 10.1016/j.tins.2004.06.004

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It is well established that genetic factors strongly contribute to the susceptibility of an individual to schizophrenia. Straub, Kendler and colleagues have published the first of several articles demonstrating a genetic association between schizophrenia and the gene encoding the dystrobrevin-binding protein dysbindin. Although no mutations in the dysbindin gene have been found, the recent identification of a specific risk haplotype in independent samples provides further evidence that dysbindin is a possible schizophrenia susceptibility gene.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects: R Medicine > R Medicine (General)
Publisher: Cell Press
ISSN: 0166-2236
Last Modified: 04 Jun 2017 05:07

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