Schizophrenia genetics: dysbindin under the microscope

Benson, Matthew A., Sillitoe, Roy V. and Blake, Derek J ORCID: https://orcid.org/0000-0002-5005-4731 2004. Schizophrenia genetics: dysbindin under the microscope. Trends in Neurosciences 27 (9) , pp. 516-519. 10.1016/j.tins.2004.06.004

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Abstract

It is well established that genetic factors strongly contribute to the susceptibility of an individual to schizophrenia. Straub, Kendler and colleagues have published the first of several articles demonstrating a genetic association between schizophrenia and the gene encoding the dystrobrevin-binding protein dysbindin. Although no mutations in the dysbindin gene have been found, the recent identification of a specific risk haplotype in independent samples provides further evidence that dysbindin is a possible schizophrenia susceptibility gene.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects:	R Medicine > R Medicine (General)
Publisher:	Cell Press
ISSN:	0166-2236
Last Modified:	24 Oct 2022 11:35
URI:	https://orca.cardiff.ac.uk/id/eprint/48671

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