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Phenotypic characterisation of Candida albicans isolated from chronic hyperplastic candidosis

Williams, David Wynne, Wilson, Melanie, Potts, Albert John Cornel and Lewis, Michael Alexander Oxenham 2000. Phenotypic characterisation of Candida albicans isolated from chronic hyperplastic candidosis. Journal of Medical Microbiology 49 (2) , pp. 199-202.

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The phenotypes of 35 Candida albicans isolates from 19 patients with chronic hyperplastic candidosis (CHC) and 35 isolates from 30 patients with non-CHC infections were compared. Typing was based on carbohydrate assimilation, chemical sensitivity and serology. Eight carbohydrate assimilation profiles were evident with the API-20C system and a single profile predominated for isolates from CHC (17 of 19 patients; 89%) and non-CHC (18 of 30 patients; 63%). Chemical sensitivity tests revealed four profiles with no significant difference between CHC and non-CHC isolates. Serotype A predominated for isolates from both CHC (15 of 19 patients; 79%) and non-CHC (25 of 30 patients; 83%) infections. Boric acid resistance was more prevalent in CHC isolates, although a significant difference was not apparent. In summary, there was no overall difference in the phenotypes of isolates from CHC and non-CHC patients, and clonal restriction of CHC isolates was not demonstrated.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Dentistry
Subjects: R Medicine > RK Dentistry
Publisher: Pathological Society of Great Britain and Ireland
ISSN: 0022-2615
Last Modified: 15 Feb 2020 15:28

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