Phenotypic characterisation of Candida albicans isolated from chronic hyperplastic candidosis

Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131, Wilson, Melanie ORCID: https://orcid.org/0000-0002-8834-8268, Potts, Albert John Cornel and Lewis, Michael Alexander Oxenham ORCID: https://orcid.org/0000-0003-1917-0651 2000. Phenotypic characterisation of Candida albicans isolated from chronic hyperplastic candidosis. Journal of Medical Microbiology 49 (2) , pp. 199-202.

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Abstract

The phenotypes of 35 Candida albicans isolates from 19 patients with chronic hyperplastic candidosis (CHC) and 35 isolates from 30 patients with non-CHC infections were compared. Typing was based on carbohydrate assimilation, chemical sensitivity and serology. Eight carbohydrate assimilation profiles were evident with the API-20C system and a single profile predominated for isolates from CHC (17 of 19 patients; 89%) and non-CHC (18 of 30 patients; 63%). Chemical sensitivity tests revealed four profiles with no significant difference between CHC and non-CHC isolates. Serotype A predominated for isolates from both CHC (15 of 19 patients; 79%) and non-CHC (25 of 30 patients; 83%) infections. Boric acid resistance was more prevalent in CHC isolates, although a significant difference was not apparent. In summary, there was no overall difference in the phenotypes of isolates from CHC and non-CHC patients, and clonal restriction of CHC isolates was not demonstrated.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Dentistry
Subjects:	R Medicine > RK Dentistry
Publisher:	Pathological Society of Great Britain and Ireland
ISSN:	0022-2615
Last Modified:	25 Oct 2022 10:04
URI:	https://orca.cardiff.ac.uk/id/eprint/61071

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