Early dengue virus infection in human skin: a cycle of inflammation and infectivity [Commentary]

Ivory, Matthew Owen ORCID: https://orcid.org/0000-0002-8736-395X, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Piguet, Vincent 2015. Early dengue virus infection in human skin: a cycle of inflammation and infectivity [Commentary]. Journal of Investigative Dermatology 135 (7) , pp. 1711-1712. 10.1038/jid.2014.544

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Abstract

Early events during dengue virus (DENV) infection remain poorly understood. In this issue, Schaeffer and colleagues employ ex vivo human skin cells to investigate viral infection. They show that skin-resident immune cells are infected by DENV and that their infectability is increased in the inflammatory skin conditions (especially those in which IL-4 is released) that accompany the mosquito bites transmitting the virus.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine Schools > Pharmacy Research Institutes & Centres > Systems Immunity Research Institute (SIURI)
Publisher:	Nature Publishing Group
ISSN:	0022-202X
Date of First Compliant Deposit:	30 March 2016
Date of Acceptance:	23 December 2014
Last Modified:	16 Nov 2024 09:45
URI:	https://orca.cardiff.ac.uk/id/eprint/74279

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