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Potts, Matthew R., Evans, Sam L. ORCID: https://orcid.org/0000-0003-3664-2569, Pullin, Rhys ORCID: https://orcid.org/0000-0002-2853-6099, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 and Wyatt, Hayley 2023. An analysis of the relationship between microneedle spacing, needle force and skin strain during the indentation phase prior to skin penetration. Computer Methods in Biomechanics and Biomedical Engineering 26 (14) , pp. 1719-1731. 10.1080/10255842.2022.2136486
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Dul, Maria ORCID: https://orcid.org/0000-0002-0192-2280, Alali, Mohammed, Ameri, Mahmoud, Burke, Matthew Douglas, Craig, Christine M., Creelman, Benjamin Paul, Dick, Lisa, Donnelly, Ryan F., Eakins, Michael N., Frivold, Collrane, Forster, Angus Harry, Gilbert, Philippe-Alexandre, Henke, Stefan, Henry, Sebastien, Hunt, Desmond, Lewis, Hayley, Maibach, Howard I., Mistilis, Jessica Joyce, Park, Jung-Hwan, Prausnitz, Mark R., Robinson, David Kenneth, Hernandez, Carmen Amelia Rodriguez, Ross, Charles, Shin, Juyeop, Speaker, Tycho Joseph, Taylor, Kevin Michael, Zehrung, Darin, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Jarrahian, Courtney and Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584 2023. Assessing the risk of a clinically significant infection from a Microneedle Array Patch (MAP) product. Journal of Controlled Release 361 , pp. 236-245. 10.1016/j.jconrel.2023.07.001
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Massufero Vergilio, Mariane, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Lauro Lima, Lonetá, Alvarenga Rezende, Rodrigo and Ricci Leonardi, Gislaine 2023. Drug delivery systems based in microneedles for dermatological diseases and aesthetic enhancement. Current Medicinal Chemistry 30 10.2174/0929867330666230525122913
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Azizova, Liana, Morgan, David ORCID: https://orcid.org/0000-0002-6571-5731, Rowlands, Jeff, Brousseau, Emmanuel ORCID: https://orcid.org/0000-0003-2728-3189, Kulik, Tetiana, Palianytsia, Borys, Mansell, Jason Peter, Birchall, James ORCID: https://orcid.org/0000-0001-8521-6924, Wilkinson, Thomas ORCID: https://orcid.org/0000-0003-0397-6079, Sloan, Alastair ORCID: https://orcid.org/0000-0002-1791-0903 and Nishio Ayre, Wayne ORCID: https://orcid.org/0000-0003-2405-1876 2022. Parameters controlling octadecyl phosphonic acid self-assembled monolayers on titanium dioxide for anti-fouling biomedical applications. Applied Surface Science 604 , 154462. 10.1016/j.apsusc.2022.154462
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Howells, Olivia, Blayney, Gareth J., Gualeni, Benedetta ORCID: https://orcid.org/0000-0002-5216-1151, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Eng, Pey F., Ashraf, Huma, Sharma, Sanjiv and Guy, Owen J. 2022. Design, fabrication, and characterisation of a silicon microneedle array for transdermal therapeutic delivery using a single step wet etch process. European Journal of Pharmaceutics and Biopharmaceutics 171 , pp. 19-28. 10.1016/j.ejpb.2021.06.005
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Al Dalaty, Adnan, Gualeni, Benedetta ORCID: https://orcid.org/0000-0002-5216-1151, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 2022. Models and methods to characterise levonorgestrel release from intradermally administered contraceptives. Drug Delivery and Translational Research 12 , pp. 335-349. 10.1007/s13346-021-01091-5
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Tatovic, D. ORCID: https://orcid.org/0000-0002-3879-2686, McAteer, M. A., Barry, J., Barrientos, A., Rodríguez Terradillos, K., Perera, I., Kochba, E., Levin, Y., Dul, M., Coulman, S. A. ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, J. C. ORCID: https://orcid.org/0000-0001-8521-6924, von Ruhland, C., Howell, A., Stenson, R., Alhadj Ali, M., Luzio, S. D., Dunseath, G., Cheung, W. Y., Holland, G., May, K., Ingram, J. R. ORCID: https://orcid.org/0000-0002-5257-1142, Chowdhury, M. M. U., Wong, F. S. ORCID: https://orcid.org/0000-0002-2812-8845, Casas, R., Dayan, C. ORCID: https://orcid.org/0000-0002-6557-3462 and Ludvigsson, J. 2022. Safety of the use of gold nanoparticles conjugated with proinsulin peptide and administered by hollow microneedles as an immunotherapy in Type 1 diabetes. Immunotherapy Advances 2 (1) , ltac002. 10.1093/immadv/ltac002
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Gualeni, Benedetta ORCID: https://orcid.org/0000-0002-5216-1151, Hughes, Louise, Stauber, Isabelle, Ackers, Louise, Gorman, Angela, Gashuga, Dorothy, Dzabala, Nettie, Chimimba, Frider, Chikowe, Ibrahim, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 2021. Human-centred design of a new microneedle-based hormonal contraceptive delivery system [version 2; peer review: 2 approved with reservations]. Gates Open Research 5 , 96. 10.12688/gatesopenres.13233.2
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Nishio Ayre, Wayne ORCID: https://orcid.org/0000-0003-2405-1876, Scully, Nicole, Elford, Carole, Evans, Bronwen AJ ORCID: https://orcid.org/0000-0003-3664-2569, Rowe, Wendy, Rowlands, Jeff, Mitha, Ravi, Malpas, Paul, Manti, Panagiota, Holt, Cathy ORCID: https://orcid.org/0000-0002-0428-8078, Morgan-Jones, Rhidian, Birchall, James ORCID: https://orcid.org/0000-0001-8521-6924, Denyer, Stephen P and Evans, Sam L ORCID: https://orcid.org/0000-0003-3664-2569 2021. Alternative radiopacifiers for polymethyl methacrylate bone cements: Silane-treated anatase titanium dioxide and yttria-stabilised zirconium dioxide. Journal of Biomaterials Applications 35 (10) , pp. 1235-1252. 10.1177/0885328220983797
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Singh, Ravinder K., Malosse, Camille, Davies, Joanne, Malissen, Bernard, Kochba, Efrat, Levin, Yotam, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Coulman, Sion A ORCID: https://orcid.org/0000-0002-1277-7584, Mous, Jan, McAteer, Martina A., Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462, Henri, Sandrine and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2021. Using gold nanoparticles for enhanced intradermal delivery of poorly soluble auto-antigenic peptides. Nanomedicine: Nanotechnology, Biology and Medicine 32 , 102321. 10.1016/j.nano.2020.102321
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Ingrole, Rohan S.J., Azizoglu, Erkan, Dul, Maria ORCID: https://orcid.org/0000-0002-0192-2280, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Gill, Harvinder S. and Prausnitz, Mark R. 2021. Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity. Biomaterials 267 , 120491. 10.1016/j.biomaterials.2020.120491
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Tyrrell, Victoria J., Ali, Faraz, Boeglin, William E., Andrews, Robert, Burston, James, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Ingram, John R., Murphy, Robert C., Piguet, Vincent, Brash, Alan R., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 2021. Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions. Journal of Lipid Research 62 , 100094. 10.1016/j.jlr.2021.100094
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Bolton, Chris J. W., Howells, Olivia, Blayney, Gareth J., Eng, Pey F., Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Gualeni, Benedetta ORCID: https://orcid.org/0000-0002-5216-1151, Roberts, Kerry, Ashraf, Huma and Guy, Owen J. 2020. Hollow silicon microneedle fabrication using advanced plasma etch technologies for applications in transdermal drug delivery. Lab on a Chip 20 (15) , pp. 2788-2795. 10.1039/D0LC00567C
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Arikat, Farah ORCID: https://orcid.org/0000-0001-5300-6009, Hanna, Stephanie J., Singh, Ravinder K., Vilela, Luciano, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 2020. Targeting proinsulin to local immune cells using an intradermal microneedle delivery system; a potential antigen-specific immunotherapy for type 1 diabetes. Journal of Controlled Release 322 , pp. 593-601. 10.1016/j.jconrel.2020.02.031
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Maarifi, Ghizlane, Czubala, Magdalena ORCID: https://orcid.org/0000-0001-9881-1095, Lagisquet, Justine, Ivory, Matthew ORCID: https://orcid.org/0000-0002-8736-395X, Fuchs, Kyra, Papin, Laure, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Nisole, Sebastien, Piguet, Vincent and Blanchet, Fabien P. 2019. Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells. Cellular and Molecular Immunology 17 , pp. 547-549. 10.1038/s41423-019-0302-5
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Dul, M. ORCID: https://orcid.org/0000-0002-0192-2280, Nikolic, T., Stefanidou, M., McAteer, M.A., Williams, P., Mous, J., Roep, B.O., Kochba, E., Levin, Y., Peakman, M., Wong, F.S. ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, C.M. ORCID: https://orcid.org/0000-0002-6557-3462, Tatovic, D. ORCID: https://orcid.org/0000-0002-3879-2686, Coulman, S.A. ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, J.C. ORCID: https://orcid.org/0000-0001-8521-6924 2019. Conjugation of a peptide autoantigen to gold nanoparticles for intradermally administered antigen specific immunotherapy. International Journal of Pharmaceutics 562 , pp. 303-312. 10.1016/j.ijpharm.2019.03.041
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Price, Annie, Rai, Simran, McLeod, Robert ORCID: https://orcid.org/0000-0003-3221-6896, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 and Elhassan, Hassan 2018. Topical propranolol for infantile haemangiomas: A systematic review. Journal of the European Academy of Dermatology and Venereology 32 (12) , pp. 2083-2089. 10.1111/jdv.14963
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Gualeni, B. ORCID: https://orcid.org/0000-0002-5216-1151, Coulman, S. A. ORCID: https://orcid.org/0000-0002-1277-7584, Shah, D., Eng, P.F., Ashraf, H., Vescovo, P., Blayney, G.J., Piveteau, L.-D., Guy, O.J. and Birchall, J.C. ORCID: https://orcid.org/0000-0001-8521-6924 2018. Minimally-invasive and targeted therapeutic cell delivery to the skin using microneedle devices. British Journal of Dermatology 178 (3) , pp. 731-739. 10.1111/bjd.15923
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Davies, Lleucu, Gateley, Christopher, Holland, Phillip, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, James ORCID: https://orcid.org/0000-0001-8521-6924 2018. Accelerating topical anaesthesia using microneedles. Skin Pharmacology and Physiology 30 (6) , pp. 277-283. 10.1159/000479530
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Moreno, Esther, Schwartz, Juana, Calvo, Alba, Blanco, Laura, Larrea, Esther, Irache, Juan M, Sanmartín, Carmen, Coulman, Sion A ORCID: https://orcid.org/0000-0002-1277-7584, Soto, Manuel, Birchall, James C ORCID: https://orcid.org/0000-0001-8521-6924 and Espuelas, Socorro 2017. Skin vaccination using microneedles coated with a plasmid DNA cocktail encoding nucleosomal histones of Leishmania spp. International Journal of Pharmaceutics 533 (1) , pp. 236-244. 10.1016/j.ijpharm.2017.09.055
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Dul, M. ORCID: https://orcid.org/0000-0002-0192-2280, Stefanidou, M.., Porta, P., Serve, J., O'Mahony, C., Malissen, B., Henri, S., Levin, Y., Kochba, E., Wong, F.S. ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, C. ORCID: https://orcid.org/0000-0002-6557-3462, Coulman, S.A. ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, J.C. ORCID: https://orcid.org/0000-0001-8521-6924 2017. Hydrodynamic gene delivery in human skin using a hollow microneedle device. Journal of Controlled Release 265 , pp. 120-131. 10.1016/j.jconrel.2017.02.028
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Zhao, Xin, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Hanna, Stephanie J., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462 and Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 2017. Formulation of hydrophobic peptides for skin delivery via coated microneedles. Journal of Controlled Release 265 , pp. 2-13. 10.1016/j.jconrel.2017.03.015
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McGrath, Marie, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 and Prausnitz, Mark 2017. Editorial. Journal of Controlled Release 265 , p. 1. 10.1016/j.jconrel.2017.10.030
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Martin, Christopher, Alcock, Natalie, Hiom, Sarah and Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 2017. Development and evaluation of topical gabapentin formulations. Pharmaceutics 9 (3) , p. 31. 10.3390/pharmaceutics9030031
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Jones, Brian, Ecenarro, Susana, Whiteside, Ben, Birchall, James ORCID: https://orcid.org/0000-0001-8521-6924 and Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584 2017. Imaging techniques for dry powder inhaler capsules. Inhalation
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Nishio Ayre, Wayne ORCID: https://orcid.org/0000-0003-2405-1876, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Evans, Samuel L. ORCID: https://orcid.org/0000-0003-3664-2569 and Denyer, Stephen P. 2016. A novel liposomal drug delivery system for PMMA bone cements. Journal of Biomedical Materials Research Part B: Applied Biomaterials 104 (8) , pp. 1510-1524. 10.1002/jbm.b.33488
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Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095, Finsterbusch, Katja, Ivory, Matthew O. ORCID: https://orcid.org/0000-0002-8736-395X, Mitchell, J. Paul, Ahmed, Zahra, Shimauchi, Takatoshi, Karoo, Richard O. S., Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Gateley, Christopher, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Blanchet, Fabien P. and Piguet, Vincent 2016. TGFβ induces a SAMHD1-independent post-entry restriction to HIV-1 infection of human epithelial Langerhans cells. Journal of Investigative Dermatology 136 (10) , pp. 1981-1989. 10.1016/j.jid.2016.05.123
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Caucheteux, Stephan M., Mitchell, John P., Ivory, Matthew O. ORCID: https://orcid.org/0000-0002-8736-395X, Hirosue, Sachiko, Hakobyan, Svetlana, Dolton, Garry, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Kan-Mitchell, June, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Nestle, Frank, Moris, Arnaud, Karoo, Richard O., Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Swartz, Melody A., Hubbel, Jeffrey A., Blanchet, Fabien P. and Piguet, Vincent 2016. Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1. Journal of Investigative Dermatology 136 (6) , pp. 1172-1181. 10.1016/j.jid.2016.01.033
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Teagle, Alexandra R., Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832 2016. Gene therapy for pyoderma gangrenosum: optimal transfection conditions and effect of drugs on gene delivery in the HaCaT cell line using cationic liposomes. Skin Pharmacology and Physiology 29 , pp. 119-129. 10.1159/000444859
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Chong, Rosalind Hui, Jones, Brian, Díez, Fernando, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584 2016. Evaluating the sensitivity, reproducibility and flexibility of a method to test hard shell capsules intended for use in dry powder inhalers. International Journal of Pharmaceutics 500 (1-2) , pp. 316-325. 10.1016/j.ijpharm.2016.01.034
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Zhao, Xin, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Tatovic, Danijela ORCID: https://orcid.org/0000-0002-3879-2686, Singh, Ravinder K., Wen, Li, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462 and Hanna, Stephanie J. 2016. Microneedle delivery of autoantigen for immunotherapy in type 1 diabetes. Journal of Controlled Release 223 , pp. 178-187. 10.1016/j.jconrel.2015.12.040
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Alhadj Ali, Mohammad ORCID: https://orcid.org/0000-0002-9780-6443, Thrower, Sally L., Hanna, Stephanie J., Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 and Tatovic, Danijela ORCID: https://orcid.org/0000-0002-3879-2686 2015. Topical steroid therapy induces pro-tolerogenic changes in Langerhans cells in human skin. Immunology 146 (3) , pp. 411-422. 10.1111/imm.12518
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Choi, Heungjae ORCID: https://orcid.org/0000-0003-1108-293X, Naylon, Jack, Luzio, Steve, Buetler, Jan, Birchall, James ORCID: https://orcid.org/0000-0001-8521-6924, Martin, Chris and Porch, Adrian ORCID: https://orcid.org/0000-0001-5293-8883 2015. Design and in vitro interference test of microwave noninvasive blood glucose monitoring sensor. IEEE Transactions on Microwave Theory and Techniques 63 (10) , pp. 3016-3025. 10.1109/TMTT.2015.2472019
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Ivory, Matthew Owen ORCID: https://orcid.org/0000-0002-8736-395X, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Piguet, Vincent 2015. Early dengue virus infection in human skin: a cycle of inflammation and infectivity [Commentary]. Journal of Investigative Dermatology 135 (7) , pp. 1711-1712. 10.1038/jid.2014.544
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Rattanapak, Teerawan, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Young, Katherine, Kubo, Atsuko, Fujimori, Sayumi, Ishii, Masaru and Hook, Sarah 2014. Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization. PLOS ONE 9 (2) , e89503. 10.1371/journal.pone.0089503
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Rattanapak, Teerawan, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Young, Katherine, Ishii, Masaru, Meglinski, Igor, Rades, Thomas and Hook, Sarah 2013. Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy. Journal of Controlled Release 172 (3) , pp. 894-903. 10.1016/j.jconrel.2013.08.018

Pearton, Marc, Pirri, Daniela, Kang, Sang-Moo, Compans, Richard W. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2013. Host responses in human skin after conventional intradermal injection or microneedle administration of virus-like-particle influenza vaccine. Advanced Healthcare Materials 2 (10) , pp. 1401-1410. 10.1002/adhm.201300006

Chong, Rosalind, Gonzalez-Gonzalez, E., Lara, Maria F., Speaker, Tycho J., Contag, Christopher H., Kaspar, Roger L., Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832 and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2013. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. Journal of Controlled Release 166 (3) , pp. 211-219. 10.1016/j.jconrel.2012.12.030

Tatovic, Danijela ORCID: https://orcid.org/0000-0002-3879-2686, Pearton, Marc, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Wong, S. and Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 2013. Topical steroid has the potential of modulating skin dendritic cells to tolerogenic antigen presenting cells in human organ skin bath culture [Abstract]. Diabetic Medicine 30 (s1) , p. 53. 10.1111/dme.12091_1

Groves, Rachel Beth, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Evans, Samuel Lewin ORCID: https://orcid.org/0000-0003-3664-2569 2013. An anisotropic, hyperelastic model for skin: experimental measurements, finite element modelling and identification of parameters for human and murine skin. Journal of the Mechanical Behaviour of Biomedical Materials 18 , pp. 167-180. 10.1016/j.jmbbm.2012.10.021

Torrisi, Barbara Maria, Zarnitsyn, V., Prausnitz, M. R., Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Gateley, Christopher, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584 2013. Pocketed microneedles for rapid delivery of a liquid-state botulinum toxin A formulation into human skin. Journal of Controlled Release 165 (2) , pp. 146-152. 10.1016/j.jconrel.2012.11.010

Torrisi, Barbara Maria, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Jones, Brian, Díez, Fernando and Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584 2013. The development of a sensitive methodology to characterise hard shell capsule puncture by dry powder inhaler pins. International Journal of Pharmaceutics 456 (2) , pp. 545-552. 10.1016/j.ijpharm.2013.08.011

Chong, Rosalind H.E., Gonzalez-Gonzalez, Emilio, Lara, Maria F., Speaker, Tycho J., Contag, Christopher H., Kaspar, Roger L., Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832 and Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 2013. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. Journal of Controlled Release 166 (3) , p. 211. 10.1016/j.jconrel.2012.12.030

Yildiz, Ayca, John, Elinor, Özsoy, Yildiz, Araman, Ahmet, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Broadley, Kenneth John ORCID: https://orcid.org/0000-0002-3339-2050 and Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X 2012. Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation. Journal of Controlled Release 162 (2) , pp. 456-463. 10.1016/j.jconrel.2012.07.008

Birchall, James Cardaoc ORCID: https://orcid.org/0000-0001-8521-6924 2012. Overcoming the stratum corneum barrier: microneedle delivery of macromolecules and vaccines [Abstract]. International Journal of Cosmetic Science 34 (4) , p. 361. 10.1111/j.1468-2494.2012.00720.x

Pearton, Marc, Saller, Verena, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Gateley, Chris, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Zarnitsyn, Vladimir and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2012. Microneedle delivery of plasmid DNA to living human skin: Formulation coating, skin insertion and gene expression. Journal of Controlled Release 160 (3) , pp. 561-569. 10.1016/j.jconrel.2012.04.005

Martin, Christopher, Allender, Christopher John, Brain, Keith Roger, Morrissey, A. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2012. Low temperature fabrication of biodegradable sugar glass microneedles for transdermal drug delivery applications. Journal of Controlled Release 158 (1) , pp. 93-101. 10.1016/j.jconrel.2011.10.024

Groves, Rachel Beth, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Evans, Samuel Lewin ORCID: https://orcid.org/0000-0003-3664-2569 2012. Quantifying the mechanical properties of human skin to optimise future microneedle device design. Computer Methods in Biomechanics and Biomedical Engineering 15 (1) , pp. 73-82. 10.1080/10255842.2011.596481

Gonzalez-Gonzalez, E., Kim, Y. C., Speaker, T. J., Hickerson, R. P., Spitler, R., Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Lara, M. F., Hu, R. H., Liang, Y. H, Kirkiles-Smith, N., Prausnitz, M. R., Milstone, L. M., Contag, C. H. and Kaspar, R. L. 2011. Visualization of plasmid delivery to keratinocytes in mouse and human epidermis. Scientific Reports 1 , p. 158. 10.1038/srep00158

Chong, Rosalind, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Saller, V., Pearton, Marc, Shah, A., Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832 and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2011. Nucleic acid delivery to skin for the potential treatment of dermatopathogenic conditions [Abstract]. Human Gene Therapy 22 (10) , A82-A82.

Teagle, Alexandra, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832 2011. The effect of drugs commonly used for pyoderma gangrenosum on the efficiency of gene transfer to human keratinocytes. Human Gene Therapy 22 (10) , A94-A94.

Smith, Mathew W. ORCID: https://orcid.org/0000-0002-5697-0204, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584 2011. The wider contribution of microbiology to the pharmaceutical sciences. Denver, Stephen P., Hodges, Norman, Gorman, Sean P. and Gilmore, Brendan F., eds. Hugo and Russell's Pharmaceutical Microbiology 8th Edition, Wiley-Blackwell, pp. 463-482.

Teagle, Alexandra, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832 2011. The effect of drugs commonly used for pyoderma gangrenosum on the efficiency of gene transfer to human keratinocytes [Abstract]. British Journal of Surgery 98 , p. 40. 10.1002/bjs.7577/abstract

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Clemo, Rachel Nerys, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144 and John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170 2011. Microneedles in clinical practice- an exploratory study into the opinions of healthcare professionals and the public. Pharmaceutical Research 28 (1) , pp. 95-106. 10.1007/s11095-010-0101-2

Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Alex, Aneesh, Pearton, Marc, Hofer, Bernd, O'Mahony, Conor, Drexler, Wolfgang and Považay, Boris 2011. In vivo, in situ imaging of microneedle insertion into the skin of human volunteers using optical coherence tomography. Pharmaceutical Research 28 (1) , pp. 66-81. 10.1007/s11095-010-0167-x

Groves, Rachel Beth, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Evans, Samuel Lewin ORCID: https://orcid.org/0000-0003-3664-2569 2011. Using inverse finite element modeling to identify the anisotropic mechanical properties of human and mouse skin in tension. Presented at: International Conference on the Mechanics of Biomaterials and Tissues, Hawaii, USA, 11-15 December 2011.

Pearton, Marc, Kang, S. M., Song, J. M., Kim, Y. C., Quan, F. S., Ivory, M., Prausnitz, M. R., Compans, R. W. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2010. Immune stimulation following microneedle delivery of influenza virus-like particle (VLP) vaccines to human skin [Abstract]. Drug Discovery Today 15 (23-24) , p. 1111.

Song, J. M., Kim, Y. C., Lipatov, A. S., Pearton, Marc, Davis, C. T., Yoo, D. G., Park, K. M., Chen, L. M., Quan, F. S., Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Donis, R. O., Prausnitz, M. R., Compans, R. W. and Kang, S. M. 2010. Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B- and T-Cell responses in mice. Clinical and Vaccine Immunology 17 (9) , pp. 1381-1389. 10.1128/CVI.00100-10
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Pearton, Marc, Kang, Sang-Moo, Song, Jae-Min, Kim, Yeu-Chun, Quan, Fu-Shi, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Ivory, Matthew Owen ORCID: https://orcid.org/0000-0002-8736-395X, Prausnitz, Mark, Compans, Richard and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2010. Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin. Vaccine 28 (37) , pp. 6104-6113. 10.1016/j.vaccine.2010.05.055

Pearton, Marc, Kang, S. M., Song, J. M., Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Ivory, Matthew Owen ORCID: https://orcid.org/0000-0002-8736-395X, Compans, R. W. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2010. Changes in human Langerhans cells following intradermal injection of influenza virus-like particle vaccines. PLoS ONE 5 (8) , e12410. 10.1371/journal.pone.0012410
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Bains, Baljinder Kaur, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Toon, Richard and Taylor, Glyn 2010. In vitro reporter gene transfection via plasm ID DNA delivered by metered dose inhaler. Journal of Pharmaceutical Sciences 99 (7) , pp. 3089-3099. 10.1002/jps.22085

Martin, Christopher, Allender, Christopher John, Brain, Keith Roger, Hodson, D. and Birchall, James ORCID: https://orcid.org/0000-0001-8521-6924 2010. Biodegradable sugar glass microneedles for macromolecular drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 62 (6) , p. 799. 10.1211/jpp.62.06.0016

Ng, K. W., Pearton, Marc, Allender, Christopher John, Morrissey, A., McLoughlin, P. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2010. Biodegradable microneedles for intra-epidermal vaccination [Abstract]. Journal of Pharmacy and Pharmacology 62 (6) , p. 798. 10.1211/jpp.62.06.0016

Ng, Keng Wooi ORCID: https://orcid.org/0000-0003-2541-4763, Pearton, Marc, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Gateley, Christopher, Morrissey, Anthony, Allender, Christopher John and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2009. Development of an ex vivo human skin model for intradermal vaccination: Tissue viability and Langerhans cell behaviour. Vaccine 27 (43) , pp. 5948-5955. 10.1016/j.vaccine.2009.07.088

Ng, Keng Wooi ORCID: https://orcid.org/0000-0003-2541-4763, Pearton, Marc, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Gateley, C., Morrissey, A., O’Mahony, C., Allender, Christopher John and Birchall, James Cardoc ORCID: https://orcid.org/0000-0001-8521-6924 2009. Tissue viability and Langerhans cell behaviour in an ex-vivo human skin model for cutaneous DNA vaccination [Abstract]. Journal of Pharmacy and Pharmacology 61 (S1) , A1-A5. 10.1211/002235709789037044

Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Gateley, Christopher, Morrissey, Anthony, McLoughlin, Peter, Allender, Christopher John and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2009. Microneedle mediated delivery of nanoparticles into human skin. International Journal of Pharmaceutics 366 (1-2) , pp. 190-200. 10.1016/j.ijpharm.2008.08.040

Haq, Mohammed-Innam-Ul, Pearton, Marc, Kalavala, Manjunatha, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, O'Mahony, C., Porter, R., John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170 and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2009. Penetration and wound-healing responses following application of microneedles and hypodermic needles to human volunteers. Journal of Pharmacy and Pharmacology 61 (S1)

Haq, Mohammed Inaam-Ul, Smith, E., John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170, Kalavala, Manjunatha, Edwards, C., Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Morrissey, A. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2009. Clinical administration of microneedles: skin puncture, pain and sensation. Biomedical Microdevices 11 (1) , pp. 35-47. 10.1007/s10544-008-9208-1

Ng, Keng Wooi ORCID: https://orcid.org/0000-0003-2541-4763, Pearton, Marc, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Anstey, Alexander Vincent, Gateley, C., Morrissey, A., Allender, Christopher John ORCID: https://orcid.org/0000-0002-6345-4144 and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2009. Ex vivo immunological studies using excised human skin. British Journal Of Dermatology 160 (4) , p. 921.

Pearton, Marc, Allender, Christopher John, Brain, Keith Roger, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Gateley, Chris, Wilke, Nicolle, Morrissey, Anthony and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2008. Gene delivery to the epidermal cells of human skin explants using microfabricated microneedles and hydrogel formulations. Pharmaceutical Research 25 (2) , pp. 407-416. 10.1007/s11095-007-9360-y

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Jones, Brian and Morrissey, A. 2008. A comparison of the puncturing properties of gelatin and hypromellose capsules for use in dry powder inhalers. Drug Development and Industrial Pharmacy 34 (8) , pp. 870-876. 10.1080/03639040801928903

Bains, Baljunder Kaur, Taylor, Glyn, Toon, R. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2007. Novel nanoparticles for pulmonary gene delivery [Abstract]. Pharmacy and Pharmacology 59 (S1) , A31-A32. 10.1211/002235707781850140

Collins, Elizabeth, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Williams, Julie L. and Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X 2007. Nuclear localisation and pDNA condensation in non-viral gene delivery. The Journal of Gene Medicine 9 (4) , pp. 265-274. 10.1002/jgm.1015

Haq, Mohammed Inaam-Ul, Smith, E., Edwards, C., Kalavala, Manjunatha, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Morrissey, A., John, David John ORCID: https://orcid.org/0000-0002-4721-6170 and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2007. An assessment of pain, penetration efficiency and trans-epidermal water loss in human subjects following application of microfabricated microneedle arrays [Abstract]. Journal of Pharmacy and Pharmacology 59 (S1) , A54. 10.1211/002235707781850168

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2007. Pulmonary delivery of nucleic acids. Expert Opinion on Drug Delivery 4 (6) , pp. 575-578. 10.1517/17425247.4.6.575

Seville, P. C., Learoyd, T. P., Li, H. Y., Williamson, I. J. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2007. Amino acid-modified spray-dried powders with enhanced aerosolisation properties for pulmonary drug delivery. Powder Technology 178 (1) , pp. 40-50. 10.1016/j.powtec.2007.03.046

Li, H.-Y. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2006. Chitosan-modified dry powder formulations for pulmonary gene delivery. Pharmaceutical Research 23 (5) , pp. 941-950. 10.1007/s11095-006-0027-x

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Gateley, Chris, Sweetland, Helen Margaret, Gershonowitz, Amikam, Neville, Lewis and Levin, Galit 2006. Cutaneous gene expression of plasmid DNA in excised human skin following delivery via microchannels created by radio frequency ablation. International Journal of Pharmaceutics 312 (1-2) , pp. 15-23. 10.1016/j.ijpharm.2005.12.036

Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Barrow, David Anthony ORCID: https://orcid.org/0000-0003-2096-7262, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Gateley, Chris, Morrissey, Anthony, Wilke, Nicolle, Allender, Christopher John, Brain, Keith Roger and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2006. Minimally invasive cutaneous delivery of macromolecules and plasmid DNA via microneedles. Current drug delivery 3 (1) , pp. 65-75.

Pearton, Marc, Gateley, C., Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Wilke, N., Morrissey, A., Allender, Christopher John, Brain, Keith Roger and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2006. Microneedle facilitated delivery of pDNA encoding HBsAg to human skin: potential for genetic vaccination [Abstract]. Journal of Pharmacy and Pharmacology 58 (S1) , A65. 10.1211/002235706778251483

Pearton, Marc, Barrow, Denise, Gateley, C., Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Wilke, N., Morrissey, A., Allender, Christopher John, Brain, Keith Roger and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2005. Hydrogels based on PLGA-PEG-PLGA triblock co-polymers as sustained release reservoirs for the delivery of pDNA to microneedle treated human skin [Abstract]. Journal of Pharmacy and Pharmacology 57 (S1) , S83-S84. 10.1211/002235705778248352

Li, H.-Y., Jeans, Christopher, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Taylor, Glyn 2005. Nanoparticles for pulmonary drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 57 (S1) , S20. 10.1211/002235705778248569

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Pearton, Marc, Allender, Christopher John, Brain, Keith Roger, Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144, Gateley, Chris, Wilke, Nicolle and Morrissey, Anthony 2005. Cutaneous DNA delivery and gene expression in ex vivo human skin explants via wet-etch microfabricated microneedles. Journal of drug targeting 13 (7) , pp. 415-421. 10.1080/10611860500383705

Li, H.-Y., Seville, P. C., Williamson, I. J. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2005. The use of absorption enhancers to enhance the dispersibility of spray-dried powders for pulmonary gene therapy. The Journal of Gene Medicine 7 (8) , pp. 1035-1043. 10.1002/jgm.749

Coulman, S. A., Allender, Christopher John, Barrow, Denise, Gateley, C., Anstey, Alexander Vincent ORCID: https://orcid.org/0000-0002-6345-4144 and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2004. Microneedle facilitated cutaneous delivery of a non-viral gene complex to the viable epidermis [Abstract]. Journal of Pharmacy and Pharmacology 56 (S1) , S10-S11. 10.1211/002235704777489375

Li, H.-Y., Seville, P. C., Williamson, I. J. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2004. Dispersibility of spray-dried formulations for pulmonary drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 56 (S1) , S10. 10.1211/002235704777489375

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Bouris, K, Chabri, F and Jones,T 2004. Microfabricated silicon microneedles for nonviral cutaneous gene delivery. British Journal of Dermatology 150 (5) , pp. 869-877. 10.1111/j.1365-2133.2004.05921.x

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Kellaway, IW and Seville, PC 2002. Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying. The Journal of Gene Medicine 4 (4) , pp. 428-437. 10.1002/jgm.282

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Waterworth, C. A., Luscombe, C., Parkins, D. A. and Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X 2001. Statistical modelling of the formulation variables in non-viral gene delivery systems. Journal of Drug Targeting 9 (3) , pp. 169-184. 10.3109/10611860108997926

Ramsay, Euan, Hadgraft, Jon, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X 2000. Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro. International Journal of Pharmaceutics 210 (1-2) , pp. 97-107. 10.1016/S0378-5173(00)00571-8

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Marichal, C., Campbell, L., Alwan, A., Hadgraft, J. and Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X 2000. Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes. International Journal of Pharmaceutics 197 (1-2) , pp. 233-238. 10.1016/S0378-5173(00)00336-7

Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924, Kellaway, I. W. and Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X 2000. Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes. International Journal of Pharmaceutics 197 (1-2) , pp. 221-231. 10.1016/S0378-5173(00)00339-2

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