Hidradenitis suppurativa: an update

Ingram, John R. ORCID: https://orcid.org/0000-0002-5257-1142 2016. Hidradenitis suppurativa: an update. Clinical Medicine 16 (1) , pp. 70-73. 10.7861/clinmedicine.16-1-70

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Abstract

Hidradenitis suppurativa (HS) is a chronic, painful skin disease characterised by recurrent inflammatory lesions in flexural locations such as the axillae, groins and perineum. The papules, nodules and abscesses may discharge blood-stained pus which, combined with pain, results in marked quality-of-life reduction. Sinus tracts and scarring may also result. Onset of HS is typically in the second to fourth decades and it affects about 1% of young European adults. There are links with smoking and obesity and an autosomal dominant pattern of inheritance is reported by one-third of patients. Medical management escalates from topical antimicrobials to oral tetracyclines, a combination of clindamycin and rifampicin typically given for 10 weeks, oral disease modifiers, and anti-tumour necrosis factor-alpha therapies. Excision of individual lesions has high recurrence rates which can be minimised by wider excisions, at the expense of longer healing times. Treatment of pain is a relatively neglected aspect of therapy.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	Royal College of Physicians
ISSN:	1470-2118
Last Modified:	21 Oct 2022 07:41
URI:	https://orca.cardiff.ac.uk/id/eprint/100504

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