Complete sequence of the FII plasmid p42-2, carrying blaCTX-M-55, oqxAB, fosA3, and floR from Escherichia coli

Yang, Qiu E., Walsh, Timothy Rutland ORCID: https://orcid.org/0000-0003-4315-4096, Liu, Bao Tao, Zou, Meng Ting, Deng, Hui, Fang, Liang Xing, Liao, Xiao Ping, Sun, Jian and Liu, Ya Hong 2016. Complete sequence of the FII plasmid p42-2, carrying blaCTX-M-55, oqxAB, fosA3, and floR from Escherichia coli. Antimicrobial Agents and Chemotherapy 60 (7) , pp. 4336-4338. 10.1128/AAC.00475-16

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Abstract

We sequenced a novel conjugative multidrug resistance IncF plasmid, p42-2, isolated from Escherichia coli strain 42-2, previously identified in China. p42-2 is 106,886 bp long, composed of a typical IncFII-type backbone (∼54 kb) and one distinct acquired DNA region spanning ∼53 kb, harboring 12 antibiotic resistance genes [blaCTX-M-55, oqxA, oqxB, fosA3, floR, tetA(A), tetA(R), strA, strB, sul2, aph(3′)-II, and ΔblaTEM-1]. The spread of these multidrug resistance determinants on the same plasmid is of great concern and, because of coresistance to antibiotics from different classes, is therapeutically challenging.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	American Society for Microbiology
ISSN:	0066-4804
Date of First Compliant Deposit:	21 September 2017
Date of Acceptance:	31 March 2016
Last Modified:	20 Nov 2024 10:15
URI:	https://orca.cardiff.ac.uk/id/eprint/100804

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