Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue

Rysnik, Oliwia, McHugh, Kirsty, van Duivenvoorde, Leonie, van Tok, Melissa, Taurog, Joel, Kollnberger, Simon, Baeten, Dominique and Bowness, Paul 2016. Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue. Data in Brief 9 , pp. 100-111. 10.1016/j.dib.2016.08.046

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Abstract

Data is presented showing expression of non-conventional (NC) heavy chain forms of B27 in synovial tissues from SpA patients. Data is presented showing the expression patterns of NC-B27 in joint, gastrointestinal and lymphoid tissues from B27 transgenic (TG1) rats with M. tuberculosis-induced SpA. Expression of NC-B27 was determined by immunohistochemistry and flow cytometry using HC10 and HD6 antibodies. These data are the extension of the data presented and discussed in “Non-conventional forms of HLA-B27 are expressed in Spondyloarthritis joints and gut tissue” (O. Rysnik, K. McHugh, L. M. van Duivenvoorde, M. N. van Tok, G. Guggino, J. D. Taurog, S. Kollnberger, F. Ciccia, D. L. Baeten, P. Bowness, 2016).

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Uncontrolled Keywords:	HLA class I free-heavy chains; HLA-B27; HLA-B27 transgenic rat model; Spondyloarthropathies
Publisher:	Elsevier
ISSN:	2352-3409
Date of First Compliant Deposit:	31 May 2017
Date of Acceptance:	22 August 2016
Last Modified:	03 May 2023 22:47
URI:	https://orca.cardiff.ac.uk/id/eprint/100917

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