In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p

Kent, Nicholas A. ORCID: https://orcid.org/0000-0002-4114-1307, Karabetsou, Nickoletta, Politis, Panagiotis K. and Mellor, Jane 2001. In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p. Genes and Development 15 , pp. 619-626. 10.1101/gad.190301

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Abstract

Isw1p and Isw2p are budding yeast homologs of the DrosophilaISWI chromatin-remodeling ATPase. Using indirect-end-label and chromatin immunoprecipitation analysis, we show both independent and cooperative Isw1p- and Isw2p-mediated positioning of short nucleosome arrays in gene-regulatory elements at a variety of transcription units in vivo. We present evidence that both yeast ISWI complexes regulate developmental responses to starvation and that for Isw2p, recruitment by different DNA-binding proteins controls meiosis and haploid invasive growth.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
ISSN:	0890-9369
Date of First Compliant Deposit:	30 March 2016
Last Modified:	10 May 2023 13:47
URI:	https://orca.cardiff.ac.uk/id/eprint/1020

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