Kotecha, Sarah, Watkins, William John ORCID: https://orcid.org/0000-0003-3262-6588, Lowe, John ORCID: https://orcid.org/0000-0003-4772-1879, Henderson, A. John and Kotecha, Sailesh ORCID: https://orcid.org/0000-0003-3535-7627 2016. Effect of early-term birth on respiratory symptoms and lung function in childhood and adolescence. Pediatric Pulmonology 51 (11) , pp. 1212-1221. 10.1002/ppul.23448 |
Abstract
Background Early-term-born subjects, (37–38 weeks’ gestation), form a large part of the population and have an increased risk of neonatal respiratory morbidity and childhood respiratory symptoms; there is a paucity of data on their later lung function. We sought to (1) compare lung function at 8–9 and 14–17 years in early-term-born children with full-term-born children (39–43 weeks’ gestation); (2) assess the role of caesarean section delivery; and (3) compare respiratory symptoms and diagnosis of asthma. Methods Caucasian, singleton, term births from the Avon Longitudinal Study of Parents and Children (n = 14,062) who had lung spirometry at 8–9 (n = 5,465) and/or 14–17 (n = 3,666) years were classified as early or full term. Results At 8–9 years, standardized spirometry measures, although within the normal range, were lower in the early-term-born group, (n = 911), compared to full-term controls (n = 4,554). Delivery by caesarean section did not influence later spirometry, and the effect of early-term birth was not modified by delivery by caesarean section. At 14–17 years, the spirometry measures in the early-term group, (n = 602), were similar to the full-term group (3,064), and the rates of asthma and respiratory symptoms were also similar between the two gestation groups. Conclusions Early-term-born children had lower lung function values at 8–9 years compared to the full-term group, but were similar by 14–17 years of age. Delivery at early term should be avoided due to early and late morbidity.
Item Type: | Article |
---|---|
Date Type: | Publication |
Status: | Published |
Schools: | Medicine |
Subjects: | R Medicine > R Medicine (General) |
Publisher: | Wiley-Blackwell |
ISSN: | 8755-6863 |
Date of Acceptance: | 8 April 2016 |
Last Modified: | 15 Apr 2023 01:16 |
URI: | https://orca.cardiff.ac.uk/id/eprint/102118 |
Citation Data
Cited 12 times in Scopus. View in Scopus. Powered By Scopus® Data
Actions (repository staff only)
Edit Item |