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Clinical laboratory testing in the era of directly acting antiviral therapies for hepatitis c

Wilson, Eleanor M., Rosenthal, Elana S., Kattakuzhy, Sarah, Tang, Lydia and Kottilil, Shyam 2015. Clinical laboratory testing in the era of directly acting antiviral therapies for hepatitis c. Clinical Microbiology Reviews 30 (1) , pp. 23-42. 10.1128/CMR.00037-16

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Abstract

Directly acting antiviral (DAA) combination therapies for chronic hepatitis C virus (HCV) infection are highly effective, but treatment decisions remain complex. Laboratory testing is important to evaluate a range of viral, host, and pharmacological factors when considering HCV treatment, and patients must be monitored during and after therapy for safety and to assess the viral response. In this review, we discuss the laboratory tests relevant for the treatment of HCV infection in the era of DAA therapy, grouped according to viral and host factors.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: American Society for Microbiology
ISSN: 0893-8512
Last Modified: 05 Feb 2020 04:14
URI: https://orca.cardiff.ac.uk/id/eprint/102428

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