Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort

Mitchelmore, Philip J., Randall, Joanna, Bull, Matthew, Moore, Karen A., O'Neill, Paul A., Paszkiewicz, Konrad, Mahenthiralingam, Eshwar ORCID: https://orcid.org/0000-0001-9014-3790, Scotton, Chris J., Sheldon, Christopher D., Withers, Nicholas J. and Brown, Alan R. 2018. Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. Thorax 73 (7) , pp. 677-679. 10.1136/thoraxjnl-2016-209889

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Abstract

While Pseudomonas aeruginosa (PA) cross-infection is well documented among patients with cystic fibrosis (CF), the equivalent risk among patients with non-CF bronchiectasis (NCFB) is unclear, particularly those managed alongside patients with CF. We performed analysis of PA within a single centre that manages an unsegregated NCFB cohort alongside a segregated CF cohort. We found no evidence of cross-infection between the two cohorts or within the segregated CF cohort. However, within the unsegregated NCFB cohort, evidence of cross-infection was found between three (of 46) patients. While we do not presently advocate any change in the management of our NCFB cohort, longitudinal surveillance is clearly warranted.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Publisher:	BMJ Publishing Group
ISSN:	0040-6376
Date of First Compliant Deposit:	16 August 2017
Date of Acceptance:	14 August 2017
Last Modified:	19 Nov 2024 00:45
URI:	https://orca.cardiff.ac.uk/id/eprint/103655

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