detectRUNS: Detect runs of homozygosity and runs of heterozygosity in diploid genomes

Biscarini, Filippo ORCID: https://orcid.org/0000-0002-3901-2354, Cozzi, Paolo, Gaspa, Giustino and Marras, Gabriele 2018. detectRUNS: Detect runs of homozygosity and runs of heterozygosity in diploid genomes. CRAN (The Comprehensive R Archive Network).

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Abstract

detectRUNS is a R package for the detection of runs of homozygosity (ROH/ROHom) and of heterozygosity (ROHet, a.k.a. “heterozygosity-rich regions”) in diploid genomes. ROH/ROHom were first studied in humans (e.g. McQuillan et al. 2008) and rapidly found applications not only in human genetics abut also in animal genetics (e.g. Ferencakovic et al., 2011, in Bos taurus). More recently, the idea of looking also at “runs of heterozygosity” (ROHet or, more appropriately, “heterozygosity-rich regions”) has been proposed (Wiliams et al. 2016).

Item Type:	Other
Date Type:	Published Online
Status:	Published
Schools:	Medicine
Subjects:	Q Science > Q Science (General) Q Science > QH Natural history > QH301 Biology Q Science > QH Natural history > QH426 Genetics
Publisher:	CRAN (The Comprehensive R Archive Network)
Date of First Compliant Deposit:	6 February 2018
Last Modified:	03 Nov 2022 10:42
URI:	https://orca.cardiff.ac.uk/id/eprint/108906

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