The association of affective disorders and facial scarring: systematic review and meta-analysis

Gibson, John. A. G., Ackling, Edward, Bisson, Jonathan ORCID: https://orcid.org/0000-0001-5170-1243, Dobbs, Thomas D. and Whitaker, Iain 2018. The association of affective disorders and facial scarring: systematic review and meta-analysis. Journal of Affective Disorders 239 , pp. 1-10. 10.1016/j.jad.2018.06.013

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Abstract

Background: Facial scarring can have a dramatic effect on a patient’s psychological health and wellbeing and present unique management challenges. This patient population remains poorly characterised in the contemporary literature. Aims: To evaluate the prevalence of, and risk factors associated with affective disorders in adult patients with facial scars. Methods: A systematic review was conducted using a protocol registered with PROSPERO and in line with the PRISMA statement. A comprehensive search of the literature was conducted using PubMed, MEDLINE, EMBASE, PSYCHInfo and The Cochrane Library. Results: Twenty one studies were included, with a total of 2,394 participants. Using a random effects model, the weighted pooled prevalence of anxiety was 26.1% (95% CI 17.9%-36.3%) and the weighted pooled prevalence of depression was 21.4% (95% CI 15.4%-29.0%). Studies identified female gender, past psychiatric history and violent causation as factors associated with anxiety and depression. Limitations: Included studies were limited to those published in peer reviewed journals. Longitudinal trends in both anxiety and depression were limited by a short duration of follow up. Conclusions: There is a high and persistent burden of affective disorders in patients with facial scars. Additional research is required to further characterise this population and develop effective management strategies.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Publisher:	Elsevier
ISSN:	0165-0327
Date of First Compliant Deposit:	18 June 2018
Date of Acceptance:	4 June 2018
Last Modified:	29 Nov 2024 06:30
URI:	https://orca.cardiff.ac.uk/id/eprint/112521

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