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The association of affective disorders and facial scarring: systematic review and meta-analysis

Gibson, John. A. G., Ackling, Edward, Bisson, Jonathan ORCID:, Dobbs, Thomas D. and Whitaker, Iain 2018. The association of affective disorders and facial scarring: systematic review and meta-analysis. Journal of Affective Disorders 239 , pp. 1-10. 10.1016/j.jad.2018.06.013

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Background: Facial scarring can have a dramatic effect on a patient’s psychological health and wellbeing and present unique management challenges. This patient population remains poorly characterised in the contemporary literature. Aims: To evaluate the prevalence of, and risk factors associated with affective disorders in adult patients with facial scars. Methods: A systematic review was conducted using a protocol registered with PROSPERO and in line with the PRISMA statement. A comprehensive search of the literature was conducted using PubMed, MEDLINE, EMBASE, PSYCHInfo and The Cochrane Library. Results: Twenty one studies were included, with a total of 2,394 participants. Using a random effects model, the weighted pooled prevalence of anxiety was 26.1% (95% CI 17.9%-36.3%) and the weighted pooled prevalence of depression was 21.4% (95% CI 15.4%-29.0%). Studies identified female gender, past psychiatric history and violent causation as factors associated with anxiety and depression. Limitations: Included studies were limited to those published in peer reviewed journals. Longitudinal trends in both anxiety and depression were limited by a short duration of follow up. Conclusions: There is a high and persistent burden of affective disorders in patients with facial scars. Additional research is required to further characterise this population and develop effective management strategies.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Publisher: Elsevier
ISSN: 0165-0327
Date of First Compliant Deposit: 18 June 2018
Date of Acceptance: 4 June 2018
Last Modified: 07 Nov 2023 01:57

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