Wilton, L. A. K., Baird, Alison Lambie, Muir, Janice L., Honey, Robert Colin ![]() ![]() |
Abstract
This study sought to characterize the effects of removing the nuclei of primary importance in relaying the thalamic head direction signal to the hippocampal formation (the anterior dorsal [AD] and lateral dorsal [LD] nuclei) on the performance of a variety of spatial and nonspatial tasks. The results indicate that combined excitotoxic lesions of the AD and LD nuclei produce marked deficits on a variety of spatial tasks. These tasks included T-maze alternation and the ability to locate a hidden platform set at a fixed distance and fixed direction from a beacon in a Morris water maze. Although object recognition appeared unaffected, marked impairments were found in the ability to detect when an object was placed in a novel position (object-in-place memory).
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Biosciences Psychology Medicine Neuroscience and Mental Health Research Institute (NMHRI) |
Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
Publisher: | American Psychological Association |
ISSN: | 0735-7044 |
Last Modified: | 18 Oct 2022 12:50 |
URI: | https://orca.cardiff.ac.uk/id/eprint/11400 |
Citation Data
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