Multiple sequence-specific transcription factors modulate cytomegalovirus enhancer activity in vitro

Ghazal, Peter, Lubon, Henryk and Hennighausen, Lothar 1988. Multiple sequence-specific transcription factors modulate cytomegalovirus enhancer activity in vitro. Molecular and Cellular Biology 8 (4) , pp. 1809-1811. 10.1128/MCB.8.4.1809

Full text not available from this repository.

Abstract

The possibility of DNA-binding proteins interacting in vitro with the polymerase II transcriptional machinery was explored by using a competition assay with individual target sequences for enhancer-binding factors. Transcription factors binding to at least five specific enhancer sequences mediate the activity of the human cytomegalovirus immediate-early 1 gene in vitro. Furthermore, our data suggest that individual DNA-bound enhancer factors can interact with the promoter transcription complex.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	American Society for Microbiology
ISSN:	0270-7306
Date of Acceptance:	5 January 1988
Last Modified:	07 Sep 2018 11:15
URI:	https://orca.cardiff.ac.uk/id/eprint/114068

Citation Data

Cited 29 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item