Kamphuis, E. I., Bhattacharya, S. ![]() |
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Abstract
Since the birth of the first baby by in vitro fertilisation (IVF) in 1978, the technique has earned its reputation as a major medical breakthrough of the 20th century. IVF was developed for women with tubal disease,1 but its indications soon began to grow. In the 1990s intracytoplasmic sperm injection was developed to treat couples in which the man has poor semen quality,2 which like tubal infertility prevents sperm from coming into close proximity with an egg. In recent years, however, IVF has been applied to other types of subfertility such as mild male subfertility, endometriosis, and unexplained subfertility. The birth of many healthy children has enhanced provider and patient confidence in the safety of IVF. But does applying IVF to wider forms of infertility result in overtreatment of couples who had a reasonable chance of conceiving naturally? Is it equally effective in these conditions? And, as more is understood about the adverse health outcomes in IVF children can the risks of IVF be justified for these more liberal applications?
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Medicine |
Publisher: | BMJ Publishing Group: BMJ |
ISSN: | 0959-8138 |
Date of First Compliant Deposit: | 28 August 2018 |
Date of Acceptance: | 21 January 2014 |
Last Modified: | 04 May 2023 20:29 |
URI: | https://orca.cardiff.ac.uk/id/eprint/114436 |
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