Continuous electrochemical generator of hypervalent iodine reagents: synthetic applications in flow

Elsherbini, Mohamed, Winterson, Bethan, Alharbi, Haifa, Folgueiras Amador, Ana A., Genot, Célina and Wirth, Thomas ORCID: https://orcid.org/0000-0002-8990-0667 2019. Continuous electrochemical generator of hypervalent iodine reagents: synthetic applications in flow. Angewandte Chemie International Edition 58 (29) , pp. 9811-9815. 10.1002/anie.201904379

Preview

PDF - Accepted Post-Print Version Download (391kB) | Preview

Abstract

An efficient and reliable electrochemical generator of hypervalent iodine reagents has been developed. In the anodic oxidation of iodoarenes under flow conditions to hypervalent iodine reagents the use of electricity replaces hazardous and costly chemical oxidants. Unstable hypervalent iodine reagents can be prepared easily and coupled with different substrates to achieve oxidative transformations in high yields. The unstable electrochemically generated reagents can also easily be transformed into classic bench stable hypervalent iodine reagents via ligand exchange. The combination of electrochemical and flow chemistry advantages largely improves the ecological footprint of the overall process compared to conventional approaches.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Publisher:	Wiley
ISSN:	1433-7851
Date of First Compliant Deposit:	14 May 2019
Date of Acceptance:	3 May 2019
Last Modified:	06 Nov 2024 03:15
URI:	https://orca.cardiff.ac.uk/id/eprint/122438

Citation Data

Cited 107 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item