Facile, mild and efficient synthesis of azines using phosphonic dihydrazide

Khidre, Rizk E., Mohamed, Hanan A., Kariuki, Benson M. ORCID: https://orcid.org/0000-0002-8658-3897 and El-Hiti, Gamal A. 2020. Facile, mild and efficient synthesis of azines using phosphonic dihydrazide. Phosphorus, Sulfur, and Silicon and the Related Elements 195 (1) , pp. 29-36. 10.1080/10426507.2019.1633531

Preview

PDF - Accepted Post-Print Version Download (540kB) | Preview

Abstract

Several bis(N'-arylpropanehydrazonoyl chlorides) were synthesized in good yields from condensation reactions of hydrazonoyl chlorides and phosphonic dihydrazide. Under the conditions employed, none of the expected phosphorylhydrazines were isolated. Nucleophilic substitution of bis(N'-arylpropanehydrazonoyl chlorides) with thiophenol, sodium phenylsulfinate, hydroxyl amine, and piperidine afforded the corresponding azines. Similarly, 1,2-bis(heteroaryl)ethylidene)hydrazines were produced from reaction of phosphonic dihydrazide and heteroaryl methyl ketones. The structures of the products were confirmed by NMR and IR spectral data along with X-ray crystal structure determination and their purities were confirmed by the elemental analyses.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Publisher:	Taylor & Francis
ISSN:	1042-6507
Date of First Compliant Deposit:	10 July 2019
Date of Acceptance:	15 June 2019
Last Modified:	27 Nov 2024 10:30
URI:	https://orca.cardiff.ac.uk/id/eprint/124115

Citation Data

Cited 3 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item