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Double or nothing? Cell division and cell size control

Jones, Angharad R. ORCID:, Band, Leah R. and Murray, James A. H. ORCID: 2019. Double or nothing? Cell division and cell size control. Trends in Plant Science 24 (12) , pp. 1083-1093. 10.1016/j.tplants.2019.09.005

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Size is a fundamental property that must be tightly regulated to ensure that cells and tissues function efficiently. Dynamic size control allows unicellular organisms to adapt to environmental changes, but cell size is also integral to multicellular development, affecting tissue size and structure. Despite clear evidence for homeostatic cell size maintenance, we are only now beginning to understand cell size regulation in the actively dividing meristematic tissues of higher plants. We discuss here how coupled advances in live cell imaging and modelling are uncovering dynamic mechanisms for size control mediated at the cellular level. We argue that integrated models of cell growth and division will be necessary to predict cell size and fully understand multicellular growth and development.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Elsevier
ISSN: 1360-1385
Funders: BBSRC
Date of First Compliant Deposit: 24 September 2019
Date of Acceptance: 6 September 2019
Last Modified: 02 May 2023 18:43

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