A novel procedure for the formation of isatins via carbonylation of lithiated N'-aryl-N,N-dimethylureas

Smith, Keith, El-Hiti, Gamal A. and Hawes, Anthony C. 1999. A novel procedure for the formation of isatins via carbonylation of lithiated N'-aryl-N,N-dimethylureas. Synlett (Supp.1) , pp. 945-947. 10.1055/s-1999-3085

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Abstract

Isatin and substituted isatins can be formed in very good yields from the appropriate N′-(2-bromoaryl)-N,N-dimethylureas via bromine-lithium exchange followed by treatment with carbon monoxide.

Item Type:	Article
Status:	Published
Schools:	Chemistry
Subjects:	Q Science > QD Chemistry
Uncontrolled Keywords:	carbonylation ; isatins ; lithiation ; ureas ; organolithiums
Additional Information:	Letter
Publisher:	Georg Thieme Verlag
ISSN:	0936-5214
Last Modified:	04 Jun 2017 02:51
URI:	https://orca.cardiff.ac.uk/id/eprint/12696

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