| Carlsen, Helle N, Degn, Hans and Lloyd, David  ORCID: https://orcid.org/0000-0002-5656-0571
      1991.
      
      Effects of alcohols on the respiration and fermentation of aerated suspensions of baker's yeast.
      Microbiology
      137
      
        (12)
      
      , 2879--2883. | 
Abstract
The immediate effects of externally added alcohols on CO2 production and O2 consumption of suspensions of washed, aerated baker's yeast were studied by stopped-flow membrane inlet mass spectrometry. Glucose-supported fermentation was progressively inhibited by increasing ethanol concentration (0-20%, v/v). The inhibition by ethanol was quite different from that observed for acetaldehyde; thus it is unlikely that toxicity of the latter can account for the observed effects. For five different alkanols (methanol, ethanol, I-propanol, 2-propanol and I-butanol) increasing inhibition of anaerobic fermentation was correlated with increased partition coefficients into a hydrophobic milieu. This suggests that the action of ethanol is primarily located at a hydrophobic site, possibly at a membrane. Results for respiratory activities were not as definite as for those for anaerobic metabolism because some alkanols act as respiratory substrates as well as giving inhibitory effects.
| Item Type: | Article | 
|---|---|
| Date Type: | Published Online | 
| Status: | Published | 
| Schools: | Schools > Biosciences | 
| Publisher: | Microbiology Society | 
| ISSN: | 1350-0872 | 
| Date of Acceptance: | 5 September 1991 | 
| Last Modified: | 26 Oct 2022 08:33 | 
| URI: | https://orca.cardiff.ac.uk/id/eprint/127761 | 
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