Bates, Sarah, Odd, David ORCID: https://orcid.org/0000-0002-6416-4966, Luyt, Karen, Mannix, Paul, Wach, Richard, Evans, David and Heep, Axel 2016. Superior vena cava flow and intraventricular haemorrhage in extremely preterm infants. Journal of Maternal-Fetal and Neonatal Medicine 29 (10) , pp. 1581-1587. 10.3109/14767058.2015.1054805 |
Abstract
bjective: To evaluate the relationship between superior vena cava flow (SVCF) measurements within the first 24 h of life, and development of intraventricular haemorrhage (IVH) in extremely preterm infants. Study design: Single centre retrospective cohort study of 108 preterm infants born less than 28 weeks’ gestation. Main outcome measure was degree of IVH at day 7 postnatal age. Results: The mean GA of the study group was 25.4 weeks. Mean SVCF was lower (75 ml/kg/min) in infants later diagnosed with IVH (n = 46) compared to infants, who did not develop IVH (87.7 ml/kg/min, p = 0.055). PDA diameter was inversely associated with SVCF (p = 0.024) and reversal of flow in the descending aorta (p = 0.001). Sensitivity analysis did not confirm an independent association of SVCF with development of IVH [OR 0.990 (0.978–1.002), p = 0.115]. Conclusion: Our study describes early SVCF in extremely preterm infants is associated with the extent of ductal shunting, but insensitive in predicting IVH.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Medicine |
Publisher: | Informa Healthcare |
ISSN: | 1476-7058 |
Date of Acceptance: | 21 May 2015 |
Last Modified: | 07 Nov 2022 10:43 |
URI: | https://orca.cardiff.ac.uk/id/eprint/133346 |
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