Norris, Joseph M., Allen, Clare, Ball, Rhys, Freeman, Alex, Giganti, Francesco, Kelly, Daniel  ORCID: https://orcid.org/0000-0002-1847-0655, Kirkham, Alex, Simpson, Benjamin S., Stavrinides, Vasilis, Whitaker, Hayley C. and Emberton, Mark
2021.
Prostate cancer undetected by mpMRI: tumor conspicuity is reliant upon optimal scan timing and quality.
Urology
148
, pp. 316-317.
10.1016/j.urology.2020.11.037
|
Preview |
PDF
- Accepted Post-Print Version
Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (101kB) | Preview |
Abstract
We commend Alanee et al for their detailed description of prostate cancers not detected by multiparametric magnetic resonance imaging (mpMRI). 1 They analyzed radical prostatectomy findings for 33 men lacking mpMRI-conspicuous prostate cancer (defined as Prostate Imaging Reporting and Data System [PI-RADS] scores 1-2) on preoperative mpMRI. They found 27% (9/33) of men with negative mpMRI had Gleason Grade Group (GGG) 3-5 cancer at prostatectomy, including 9 with extraprostatic extension, and 1 with Gleason grade 5 + 5 disease. Ostensibly, these findings are at odds with contemporary evidence in which mpMRI-invisible disease harbors reassuring molecular and histopathological features (ie, overall GGG ≤2). 2 , 3 We believe that this discrepancy is attributable to certain methodological concerns, including quality of mpMRI acquisiton. 4
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Healthcare Sciences |
| Publisher: | Elsevier |
| ISSN: | 0090-4295 |
| Date of First Compliant Deposit: | 31 March 2021 |
| Last Modified: | 04 Dec 2024 22:45 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/136839 |
Citation Data
Cited 1 time in Scopus. View in Scopus. Powered By Scopus® Data
Actions (repository staff only)
 |
Edit Item |
Dimensions
Dimensions