Bera, Milan, Modak, Atanu, Patra, Tuhin, Maji, Arun and Maiti, Debabrata 2014. Meta-selective arene C–H bond olefination of arylacetic acid using a nitrile-based directing group. Organic Letters 16 (21) , pp. 5760-5763. 10.1021/ol502823c |
Official URL: http://dx.doi.org/10.1021/ol502823c
Abstract
A nitrile-based template attached with a phenylacetic acid framework promoted meta-selective C–H bond olefination. This palladium-catalyzed protocol is applicable to a wide range of substituted phenylacetic acids and tolerates a variety of functional groups. The versatility of this operationally simple method has been demonstrated through drug diversification.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Publisher: | American Chemical Society |
ISSN: | 1523-7060 |
Last Modified: | 06 May 2023 01:58 |
URI: | https://orca.cardiff.ac.uk/id/eprint/138424 |
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