Copper mediated decarboxylative direct C-H arylation of heteroarenes with benzoic acids

Patra, Tuhin, Nandi, Sudip, Sahoo, Santosh K. and Maiti, Debabrata 2016. Copper mediated decarboxylative direct C-H arylation of heteroarenes with benzoic acids. Chemical Communications 52 (7) , pp. 1432-1435. 10.1039/C5CC08367B

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Abstract

Decarboxylative coupling reactions to date require a stoichiometric oxidant (such as copper and silver salts) for decarboxylation purposes along with a metal catalyst (e.g. palladium) for cross-coupling. In this communication, an economic and sustainable approach by using a simple copper salt was developed in the presence of molecular oxygen as the sole oxidant. A wide range of 5-membered heteroarenes undergo aryl–heteroaryl cross-coupling with electron deficient aryl carboxylic acids.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Publisher:	Royal Society of Chemistry
ISSN:	1359-7345
Date of First Compliant Deposit:	18 February 2021
Date of Acceptance:	17 November 2015
Last Modified:	06 May 2023 04:50
URI:	https://orca.cardiff.ac.uk/id/eprint/138426

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