Acute severe asthma treated by mechanical ventilation: 10 years' experience from a district general hospital

Luksza, A. R., Smith, P. ORCID: https://orcid.org/0000-0003-4250-2562, Coakley, J., Gordan, I. J. and Atherton, S. T. 1986. Acute severe asthma treated by mechanical ventilation: 10 years' experience from a district general hospital. Thorax 41 (6) , pp. 459-463. 10.1136/thx.41.6.459

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Abstract

A retrospective study was made of patients requiring mechanical ventilation (intermittent positive pressure ventilation--IPPV) for acute severe asthma in a district general hospital during 1974-83. Thirty two patients required IPPV on 34 occasions. Complications included pneumothorax in six (18%) patients, chest infection in 12 (35%) patients, pulmonary collapse in three (9%) patients, hypotension at induction of IPPV in 12 (35%), and gastrointestinal bleeding in three (9%). Three (9%) patients died. Therapeutic bronchial lavage was performed in 19 patients. The procedure produced a rise in effective static compliance from a mean of 17 (SD 6) ml/cm H2O to 24 (9) ml/cm H2O at four hours. Bronchial lavage was associated with a significant excess of respiratory infections. A feature common to most patients was undertreatment before admission to hospital.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	BMJ Publishing Group
ISSN:	0040-6376
Last Modified:	09 Nov 2022 10:19
URI:	https://orca.cardiff.ac.uk/id/eprint/139038

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