Newborn screening for cystic fibrosis: Is there benefit for everyone?

Course, C.W. and Hanks, R. 2019. Newborn screening for cystic fibrosis: Is there benefit for everyone? Paediatric Respiratory Reviews 31 , pp. 3-5. 10.1016/j.prrv.2019.02.003

Full text not available from this repository.

Abstract

Newborn screening for cystic fibrosis (CF) has become a widely accepted and endorsed public health strategy in economically developed countries, although there is little consensus on optimal screening methods and gene panels. Increasing understanding of CFTR genetics and consequent unpredictability of phenotypic and clinical outcomes lead to diagnostic uncertainty, and emergence of Cystic Fibrosis Screen Positive Inconclusive Diagnosis (CF-SPID). Many of these children are clinically well or have a mild phenotype yet may still experience the psychosocial impact of a CF diagnosis. This questions the role of newborn screening and how best to manage those it identifies with CF-SPID.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	Elsevier
ISSN:	1526-0542
Last Modified:	20 Jul 2021 14:45
URI:	https://orca.cardiff.ac.uk/id/eprint/142572

Citation Data

Cited 6 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item