Formation and utility of reactive ketene intermediates under continuous flow conditions

Smallman, Harry R., Leitch, Jamie A., McBride, Tom, Ley, Steven V. and Browne, Duncan L. 2021. Formation and utility of reactive ketene intermediates under continuous flow conditions. Tetrahedron 93 , 132305. 10.1016/j.tet.2021.132305

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Abstract

Continuous flow systems offer unique benefits in the generation and manipulation of sensitive reactive intermediates such as ketenes. To this end, the last decade has witnessed the development of continuous flow methods for the generation of ketenes by means of chemical, thermal, and photochemical activation modes. This perspective covers these advances and the downstream reactivity of ketenes in continuous flow technology.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Additional Information:	This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Publisher:	Elsevier
ISSN:	0040-4020
Funders:	Cardiff University and EPSRC
Date of First Compliant Deposit:	19 July 2021
Date of Acceptance:	15 June 2021
Last Modified:	07 May 2023 06:12
URI:	https://orca.cardiff.ac.uk/id/eprint/142674

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