Evaluation of osteoporosis in Indian women and men using peripheral dual-energy x-ray absorptiometry (pDXA)

Anburajan, M., Kumar, D. Ashok, Sapthagirivasan, V. and Evans, William D. ORCID: https://orcid.org/0000-0003-0013-8205 2011. Evaluation of osteoporosis in Indian women and men using peripheral dual-energy x-ray absorptiometry (pDXA). Presented at: 2011 International Conference on Bioscience, Biochemistry and Bioinformatics, Sentaosa, Singapore, 26-28 Feb 2011. International Proceedings of Chemical, Biological and Environmental Engineering. Proceedings of Chemical, Biological and Environmental Engineering. , vol.5 pp. 470-474.

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Abstract

It has been claimed that osteoporosis is becoming more common in India although its prevalence in the country has not been established. Because of the lack of facilities for measurement of bone mineral density (BMD), very little population-based research on osteoporosis has been done in India. The primary objective of this study was to establish the prevalence of osteoporosis in a group of otherwise normal volunteers using forearm BMD measured by peripheral dual-energy x-ray absorptiometry (pDXA). A total of 179 Indian men and women aged 20 years or more attended a free screening camp; of these, 167 were eligible to participate in the study. Total distal forearm BMD (g cm-2) was measured using an Osteometer DTX-200 pDXA bone densitometer. Data were analyzed by dividing the participants into sex and age-specific groups and using descriptive statistics. For each participant, the T-score was calculated as the difference between BMD and the mean BMD of a group of young persons of the same sex (peak BMD), divided by the group standard deviation (SD). For both women and men, peak BMD occurred in the 20-29 year age group. The mean (±SD) values were 0.393 (±0.031) and 0.433 (±0.073) g cm-2 respectively; the difference (9.2% relative to the male mean) was significant (p=0.01, unpaired t�test). These Indian total distal forearm peak BMD values were less than published corresponding values for Japanese and Caucasian populations. In Indian women and men aged 60 years or more, mean total distal forearm BMD values were significantly reduced (by 13% and 12% respectively) compared to those obtained for women and men aged 20-40 years. Using published Osteometer DTX-200 pDXA device�specific T-score thresholds, 31.8% (7/22) of Indian women aged 50 years or more were classified as having osteoporosis (T�score ≤-2.6) while 36.4% (8/22) were found to be at risk of osteoporosis (T-score between -1.5 and -2.5). Using the same T�score thresholds, no Indian male was found to have osteoporosis but 16.7% (4/24) of men aged 50 years or more were classified as being at risk of osteoporosis.

Item Type:	Conference or Workshop Item (Paper)
Status:	Published
Schools:	Medicine
ISSN:	2010-4618
Last Modified:	09 Nov 2022 11:24
URI:	https://orca.cardiff.ac.uk/id/eprint/143066

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