Disease prevention not decolonization: a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms

Ghani, Rohma, Mullish, Benjamin H, McDonald, Julie A K, Ghazy, Anan, Williams, Horace R T, Brannigan, Eimear T, Mookerjee, Siddharth, Satta, Giovanni, Gilchrist, Mark, Duncan, Neill, Corbett, Richard, Innes, Andrew J, Pavlů, Jiří, Thursz, Mark R, Davies, Frances and Marchesi, Julian R ORCID: https://orcid.org/0000-0002-7994-5239 2021. Disease prevention not decolonization: a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms. Clinical Infectious Diseases 72 (8) , pp. 1444-1447. 10.1093/cid/ciaa948

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Abstract

Fecal microbiota transplantation (FMT) yields variable intestinal decolonization results for multidrug-resistant organisms (MDROs). This study showed significant reductions in antibiotic duration, bacteremia, and length of stay in 20 patients colonized/infected with MDRO receiving FMT (compared with pre-FMT history, and a matched group not receiving FMT), despite modest decolonization rates.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Biosciences
Publisher:	Oxford University Press
ISSN:	1058-4838
Date of First Compliant Deposit:	3 August 2021
Date of Acceptance:	4 August 2020
Last Modified:	12 May 2023 06:40
URI:	https://orca.cardiff.ac.uk/id/eprint/143125

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