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Disease prevention not decolonization: a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms

Ghani, Rohma, Mullish, Benjamin H, McDonald, Julie A K, Ghazy, Anan, Williams, Horace R T, Brannigan, Eimear T, Mookerjee, Siddharth, Satta, Giovanni, Gilchrist, Mark, Duncan, Neill, Corbett, Richard, Innes, Andrew J, Pavlů, Jiří, Thursz, Mark R, Davies, Frances and Marchesi, Julian R 2021. Disease prevention not decolonization: a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms. Clinical Infectious Diseases 72 (8) , pp. 1444-1447. 10.1093/cid/ciaa948

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Abstract

Fecal microbiota transplantation (FMT) yields variable intestinal decolonization results for multidrug-resistant organisms (MDROs). This study showed significant reductions in antibiotic duration, bacteremia, and length of stay in 20 patients colonized/infected with MDRO receiving FMT (compared with pre-FMT history, and a matched group not receiving FMT), despite modest decolonization rates.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Oxford University Press
ISSN: 1058-4838
Date of First Compliant Deposit: 3 August 2021
Date of Acceptance: 4 August 2020
Last Modified: 10 Aug 2021 16:00
URI: https://orca.cardiff.ac.uk/id/eprint/143125

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Cited 17 times in Scopus. View in Scopus. Powered By Scopus® Data

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