A web-based life-style, exercise and activity intervention for people with progressive multiple sclerosis results of a single-arm feasibility study

Busse, Monica ORCID: https://orcid.org/0000-0002-5331-5909, Playle, Rebecca ORCID: https://orcid.org/0000-0002-2989-1092, Latchem-Hastings, Julie ORCID: https://orcid.org/0000-0001-6738-916X, Button, Kate ORCID: https://orcid.org/0000-0003-1073-9901, Lowe, Rachel, Barlow, Christy ORCID: https://orcid.org/0000-0001-5759-0310, Lloyd, Barry ORCID: https://orcid.org/0000-0003-4763-1726, Dean-Young, Andrew, Poile, Vincent, Dawes, Helen, Davies, Freya ORCID: https://orcid.org/0000-0002-6956-1100, O'Halloran, Rhian, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Edwards, Adrian ORCID: https://orcid.org/0000-0002-6228-4446, Wood, Fiona ORCID: https://orcid.org/0000-0001-7397-4074 and Jones, Fiona 2022. A web-based life-style, exercise and activity intervention for people with progressive multiple sclerosis results of a single-arm feasibility study. Multiple Sclerosis and Related Disorders 57 , 103388. 10.1016/j.msard.2021.103388

PDF - Accepted Post-Print Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (378kB)

Abstract

Background People with progressive Multiple Sclerosis often struggle to access appropriate and inclusive support for regular physical activity. The Lifestyle, Exercise and Activity Package (LEAP-MS) intervention, is a co-designed web-based physical activity intervention for people with progressive Multiple Sclerosis (MS). It consists of two key components; (1) web-based physical activity coaching with physiotherapists using self-management support strategies and 2) an interactive web-based platform including a physical activity information suite, an activity selection and planning tool and a participant-physiotherapist messaging system. We aimed to evaluate recruitment, retention and uptake, in a single arm feasibility study. Methods Participants with primary or secondary progressive MS with an Expanded Disability Status Scale score of 6 to 8 were recruited. Assessments included the MS Impact Scale (MSIS-29) and measures of participation at baseline, three and six months. All participants received the intervention which consisted of up to six web-based physiotherapy- led physical activity coaching sessions alongside access to web-based education and activity suites. Recruitment, retention and uptake data were summarised. Pre-defined progression criteria were used to guide feasibility assessment. Clinical outcome data were analysed descriptively. Results Fifty-eight percent (21/36) of those submitting expressions of interest were recruited; 76% completed follow-up. Pre-specified progression criteria for retention were met but recruitment did not meet progression criteria. The intervention achieved set fidelity criteria. At three months, 12 participants (75%) reported improvements in routine activities after the intervention. MSIS-29 physical scores improved by an average of eight points (95% CI -12.6 to -3.3). Improvements were also seen in MSIS-29 psychological scores and fatigue. Some improvements were maintained at six months. Conclusions The LEAP-MS intervention is feasible and associated with improvements in MSIS-29 scores. The intervention facilitated partnership working between physiotherapists and people with progressive MS. Users developed valuable skills in supported self-management by focussing on enhancing physical activity to support overall wellbeing. This work has laid the foundations for a large-scale evaluation of a co-designed intervention with potential for far reaching impact on the lives of people with progressive MS.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Healthcare Sciences Medicine MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Publisher:	Elsevier
ISSN:	2211-0348
Date of First Compliant Deposit:	8 November 2021
Date of Acceptance:	5 November 2021
Last Modified:	06 Nov 2024 21:45
URI:	https://orca.cardiff.ac.uk/id/eprint/145376

Actions (repository staff only)

Edit Item