Fruchtman-Steinbok, Tom, Keynan, Jackob N., Cohen, Avihay, Jaljuli, Iman, Mermelstein, Shiri, Drori, Gadi, Routledge, Efrat, Krasnoshtein, Michael, Playle, Rebecca  ORCID: https://orcid.org/0000-0002-2989-1092, Linden, David E.J. ORCID: https://orcid.org/0000-0002-5638-9292 and Hendler, Talma
2021.
Amygdala electrical-finger-print (AmygEFP) NeuroFeedback guided by individually-tailored Trauma script for post-traumatic stress disorder: Proof-of-concept.
NeuroImage: Clinical
32
, 102859.
10.1016/j.nicl.2021.102859
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Abstract
Amygdala activity dysregulation plays a central role in post-traumatic stress disorder (PTSD). Hence learning to self-regulate one's amygdala activity may facilitate recovery. PTSD is further characterized by abnormal contextual processing related to the traumatic memory. Therefore, provoking the personal traumatic narrative while training amygdala down-regulation could enhance clinical efficacy. We report the results of a randomized controlled trial (NCT02544971) of a novel self-neuromodulation procedure (i.e. NeuroFeedback) for PTSD, aimed at down-regulating limbic activity while receiving feedback from an auditory script of a personal traumatic narrative. To scale-up applicability, neural activity was probed by an fMRI-informed EEG model of amygdala activity, termed Amygdala Electrical Finger-Print (AmygEFP).
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Medicine Research Institutes & Centres > Centre for Trials Research (CNTRR) |
| Additional Information: | This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/) |
| Publisher: | Elsevier |
| ISSN: | 2213-1582 |
| Date of First Compliant Deposit: | 12 November 2021 |
| Date of Acceptance: | 13 October 2021 |
| Last Modified: | 06 May 2023 13:51 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/145475 |
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