Perni, Stefano, Kong, Michael G. and Prokopovich, Polina ORCID: https://orcid.org/0000-0002-5700-9570 2012. Cold atmospheric pressure gas plasma enhances the wear performance of ultra-high molecular weight polyethylene. Acta Biomaterialia 8 (3) , pp. 1357-1365. 10.1016/j.actbio.2011.12.007 |
Abstract
Ultra-high molecular weight polyethylene (UHMWPE) is frequently employed in joint replacements because of its high biocompatibility; however, this material does not exhibit particularly strong wear performance, thus potentially reducing the longevity of such devices. Numerous techniques have been investigated to increase the resistance to wear of UHMWPE, but they are all based on expensive machinery and require a high level of safety precautions. Cold atmospheric pressure gas plasma treatment is an inexpensive process that has been used as a surface modification method and as a sterilization technique. We demonstrate for the first time that a helium/oxygen cold atmospheric pressure gas plasma can be used to enhance the wear performance of UHMWPE without affecting the cytocompatibility of the material. The exposure to a cold atmospheric pressure gas plasma results in a greater level of crosslinking of the polyethylene chains. As a consequence of the higher crosslinking, the material stiffness of the treated surface is increased.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Engineering Pharmacy |
Subjects: | R Medicine > RM Therapeutics. Pharmacology |
Uncontrolled Keywords: | cold atmospheric pressure gas plasma; total joint and disc arthroplasty; ultra-high molecular weight polyethylene; wear simulation; biomaterial modification |
Publisher: | Elsevier |
ISSN: | 1742-7061 |
Last Modified: | 18 Oct 2022 13:37 |
URI: | https://orca.cardiff.ac.uk/id/eprint/14670 |
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