Is CD38 involved in Ca2+ signalling elicited by activation of T cell receptors?

Petersen, Ole H ORCID: https://orcid.org/0000-0002-6998-0380 2022. Is CD38 involved in Ca2+ signalling elicited by activation of T cell receptors? Cell Calcium 101 , 102524. 10.1016/j.ceca.2021.102524

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Abstract

A recent publication proposes that T cell receptor activation elicits formation of the Ca2+ releasing messenger NAADP from NAADPH, catalysed by the NADPH oxidase DUOX. This is in contrast to the hitherto prevailing view that CD38 is critical for NAADP formation. Is it time to reassess the role of CD38?

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Publisher:	Elsevier
ISSN:	0143-4160
Date of First Compliant Deposit:	14 March 2022
Date of Acceptance:	21 December 2021
Last Modified:	10 Nov 2022 10:50
URI:	https://orca.cardiff.ac.uk/id/eprint/148354

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