Zhang, Huaiyuan and Wirth, Thomas  ORCID: https://orcid.org/0000-0002-8990-0667
2022.
Oxidation of BINOLs by hypervalent iodine reagents: facile synthesis of xanthenes and lactones.
Chemistry - A European Journal
28
(21)
10.1002/chem.202200181
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Abstract
Xanthene derivatives have broad applications in medicines, fluorescent probes, dyes, food additives, etc. Therefore, much attention was focused on developing the synthetic methods to prepare these compounds. Binaphthyl-based xanthene derivatives were prepared through the oxidation of BINOLs promoted by the hypervalent iodine reagent iodosylbenzene (PhIO). Nine-membered lactones were obtained through a similar oxidative reaction when iodoxybenzene (PhIO2) was used. Additionally, one-pot reactions of BINOLs, PhIO and nucleophiles such as alcohols and amines were also investigated to provide alkoxylated products and amides in good to excellent yields.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Chemistry |
| Additional Information: | This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License |
| Publisher: | Wiley |
| ISSN: | 0947-6539 |
| Funders: | China Scholarship Council |
| Date of First Compliant Deposit: | 28 March 2022 |
| Date of Acceptance: | 28 February 2022 |
| Last Modified: | 10 May 2023 10:24 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/148926 |
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