Inequality in survival of people with head and neck cancer: Head and Neck 5000 cohort study

Ingarfield, Kate ORCID: https://orcid.org/0000-0002-6910-0267, McMahon, Alex D., Hurley, Katrina, Toms, Stu, Pring, Miranda, Thomas, Steve J., Waylen, Andrea, Pawlita, Michael, Waterboer, Tim, Ness, Andy R. and Conway, David I. 2021. Inequality in survival of people with head and neck cancer: Head and Neck 5000 cohort study. Head and Neck 43 (4) , pp. 1252-1270. 10.1002/hed.26589

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Abstract

Background Explanations for socioeconomic inequalities in survival of head and neck cancer (HNC) patients have had limited attention and are not well understood. Methods The UK Head and Neck 5000 prospective clinical cohort study was analyzed. Survival relating to measures of socioeconomic status was explored including area-based and individual factors. Three-year overall survival was determined using the Kaplan–Meier method. All-cause mortality was investigated via adjusted Cox Proportional Hazard models. Results A total of 3440 people were included. Three-year overall survival was 76.3% (95% CI 74.9, 77.7). Inequality in survival by deprivation category, highest education level, and financial concerns was explained by age, sex, health, and behavioral factors. None of the potential explanatory factors fully explained the inequality associated with annual household income or the proportion of income of benefits. Conclusion These results support the interventions to address the financial issues within the wider care and support provided to HNC patients.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine Centre for Trials Research (CNTRR)
Publisher:	Wiley
ISSN:	1043-3074
Date of First Compliant Deposit:	25 April 2022
Date of Acceptance:	17 December 2020
Last Modified:	10 May 2023 13:50
URI:	https://orca.cardiff.ac.uk/id/eprint/149334

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