The PELICAN (Prematurity's Effect on the Lungs In Children and Adults Network) ERS clinical research collaboration: understanding the impact of preterm birth on lung health throughout life

Simpson, Shannon J., Hallberg, Jenny, Bates, Amber, Doyle, Lex, Halvorsen, Thomas, Hurst, John, Kotecha, Sailesh ORCID: https://orcid.org/0000-0003-3535-7627, Lombardi, Enrico, Stanojevic, Sanja and Bergstrom, Petra Um 2021. The PELICAN (Prematurity's Effect on the Lungs In Children and Adults Network) ERS clinical research collaboration: understanding the impact of preterm birth on lung health throughout life. European Respiratory Journal 57 (4) , 2004387. 10.1183/13993003.04387-2020

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Abstract

An estimated 15 million babies (∼11%) are born preterm each year (before 37 weeks of gestation), the rates of which are increasing worldwide [1]. Enhanced perinatal care, including antenatal corticosteroids, postnatal surfactant and improved respiratory management, have markedly improved survival outcomes since the 1990s, particularly for babies born very preterm (<32 weeks gestation) [1]. However, long-term pulmonary sequelae are frequent in preterm survivors and ongoing clinical management is often required. Development and severity of bronchopulmonary dysplasia (BPD), a chronic lung condition diagnosed during the neonatal period [2], is a key determinant of long-term adverse outcomes of prematurity.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	European Respiratory Society
ISSN:	0903-1936
Date of First Compliant Deposit:	31 May 2022
Date of Acceptance:	19 February 2021
Last Modified:	01 Dec 2024 09:00
URI:	https://orca.cardiff.ac.uk/id/eprint/149983

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